Evidence map›Paper›PMID 31316824›Full record

ArticleJournal of ophthalmology2019

Clinicopathological Findings of Retinoblastoma: A 10-Year Experience from a Tertiary Hospital in Kampala, Uganda.

James Joseph Yahaya, Belson Rugwizangoga, Alex Mremi, Asafu Munema

Open access · goldAbstract read
In one paragraph

Article in Journal of ophthalmology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.0field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 3 countries.

James Joseph YahayaDepartment of Pathology, Makerere College of Health Sciences, P.O. Box 7072, Kampala, Uganda.ORCID https://orcid.org/0000-0003-3647-5262
Belson RugwizangogaThe University of Rwanda, P.O. Box 4285, Kigali, Rwanda.
Alex MremiKilimanjaro Christian Medical Center (KCMC), P.O. Box 3010, Kilimanjaro, Tanzania.
Asafu MunemaOcean Road Cancer Institute (ORCI), P.O. BOX 3592, Dar-es-salaam, Tanzania.
Kilimanjaro Christian Medical Centre · TZMakerere University · UGOcean Road Cancer Institute · TZUniversity of Rwanda · RW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRetinoblastoma (RB) is one of the most common cancers occurring in young children in sub-Saharan Africa. The incidence rate reported in the literature is 9,000 new cases per year, which corresponds to 1 in 15,000 births. This study aimed at analyzing the clinicopathological findings in children with RB in Uganda. PURPOSE: The purpose of this study was to describe and analyze the clinicopathological findings in the patients with RB.

designThis was a cross-sectional analytical study involving 234 eyeball surgical specimens from 214 patients with RB diagnosed between January 2006 and December 2015.

resultsThe mean age of the patients was 27.8 months (SD = 21.413, range: 1-132 months). More than half of the cases, 50.9%, presented with leucokoria. Invasion of choroid, sclera, anterior chamber, and optic nerve was found in 26.5% (

conclusionThe majority of children with RB in Uganda present clinically with leucokoria, and their parents or guardians seek medical intervention at a later stage. Moreover, there was a noticeably significant lag period for the patients to begin treatment after the diagnosis was done.

Identifiers

PMID31316824
PMCPMC6604297
OpenAlexW2949214959

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.