Evidence map›Paper›PMID 31316759›Full record

ArticleRSC advances2019

Characterization of glycan isomers using magnetic carbon nanoparticles as a MALDI co-matrix.

Alireza Banazadeh, Reed Nieman, Mona Goli, Wenjing Peng, Ahmed Hussein, Ercan Bursal, Hans Lischka, Yehia Mechref

Abstract read
In one paragraph

Article in RSC advances, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Alireza BanazadehDepartment of Chemistry and Biochemistry, Texas Tech University, Lubbock, TX 79409-1061, USA. Email: yehia.mechref@ttu.edu; ; Tel: +1-806-742-3059.
Reed NiemanDepartment of Chemistry and Biochemistry, Texas Tech University, Lubbock, TX 79409-1061, USA. Email: yehia.mechref@ttu.edu; ; Tel: +1-806-742-3059.
Mona GoliDepartment of Chemistry and Biochemistry, Texas Tech University, Lubbock, TX 79409-1061, USA. Email: yehia.mechref@ttu.edu; ; Tel: +1-806-742-3059.
Wenjing PengDepartment of Chemistry and Biochemistry, Texas Tech University, Lubbock, TX 79409-1061, USA. Email: yehia.mechref@ttu.edu; ; Tel: +1-806-742-3059.
Ahmed HusseinDepartment of Chemistry and Biochemistry, Texas Tech University, Lubbock, TX 79409-1061, USA. Email: yehia.mechref@ttu.edu; ; Tel: +1-806-742-3059.
Ercan BursalDepartment of Nursing, School of Health, Mus Alparslan University, Mus, Turkey.
Hans LischkaDepartment of Chemistry and Biochemistry, Texas Tech University, Lubbock, TX 79409-1061, USA. Email: yehia.mechref@ttu.edu; ; Tel: +1-806-742-3059.
Yehia MechrefDepartment of Chemistry and Biochemistry, Texas Tech University, Lubbock, TX 79409-1061, USA. Email: yehia.mechref@ttu.edu; ; Tel: +1-806-742-3059.ORCID 0000-0002-6661-6073

Funding

Sensitive and Quantitative MS-bases Glycomic Mapping PlatformR01GM112490 · NIGMS · TEXAS TECH UNIVERSITY · PI MECHREF, YEHIA · 2014 to 2024
$3.2M
Quantitative Characterization of Glycopeptide IsomersR01GM130091 · NIGMS · TEXAS TECH UNIVERSITY · PI Yehia Mechref · 2019 to 2026
$2.5M
Screening of Glycan Markers in Serum for Early Detection of HCC in Different Etiologies of DiseaseU01CA225753 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI LUBMAN, DAVID M., MECHREF, YEHIA · 2018 to 2021
$2.0M
NCI NIH HHS U01 CA225753NIGMS NIH HHS R01 GM112490NIGMS NIH HHS R01 GM130091
6 · The paper itself

Abstract

Matrix-assisted laser desorption ionization-in source decay (MALDI-ISD) analysis is a useful technique in the structural analysis of glycans. Our recent publication demonstrated that magnetic carbon nanoparticles (MCNPs), used as a MALDI co-matrix, significantly enhanced ISD efficiency for glycomic analysis by MALDI-TOF. In this study, MCNPs were used for the structural study of isomeric glycans. Results from the standard glycans confirmed easy distinction of positional and linkage isomers without the need for further derivatization of glycan molecules. Extensive glycosidic and cross-ring fragmented ions provided different fragment patterns for various glycan isomers. Core- and branch-fucosylated isomers were distinguished by several unique ions, and pseudo-MS

Identifiers

PMID31316759
PMCPMC6625494

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.