Evidence map›Paper›PMID 31316601›Full record

ArticleExperimental and therapeutic medicine2019

Altered expression of leptin and leptin receptor in the development of immune-mediated aplastic anemia in mice.

Xiangcong Yin, Jie Yang, Yuhua Liu, Jian Zhang, Chunlei Xin, Hongguo Zhao, Wei Wang, Xue Shi, Zhongguang Cui, Guanglun Li and 2 more

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Experimental and therapeutic medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 53% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 1 country.

Xiangcong YinHematology Diagnosis Laboratory, The Affiliated Hospital of Qingdao University, Qingdao, Shandong 266003, P.R. China.
Jie YangHematology Diagnosis Laboratory, The Affiliated Hospital of Qingdao University, Qingdao, Shandong 266003, P.R. China.
Yuhua LiuDepartment of Medicine, Qingzhou Traditional Chinese Medicine Hospital, Weifang, Shandong 262500, P.R. China.
Jian ZhangDepartment of Hematology, Rizhao People's Hospital, Rizhao, Shandong 276800, P.R. China.
Chunlei XinDepartment of Hematology, Jining No. 1 People's Hospital, Jining, Shandong 272011, P.R. China.
Hongguo ZhaoDepartment of Hematology, The Affiliated Hospital of Qingdao University, Qingdao, Shandong 266003, P.R. China.
Wei WangDepartment of Hematology, The Affiliated Hospital of Qingdao University, Qingdao, Shandong 266003, P.R. China.
Xue ShiDepartment of Hematology, The Affiliated Hospital of Qingdao University, Qingdao, Shandong 266003, P.R. China.
Zhongguang CuiDepartment of Hematology, The Affiliated Hospital of Qingdao University, Qingdao, Shandong 266003, P.R. China.
Guanglun LiDepartment of Hematology, The Affiliated Hospital of Qingdao University, Qingdao, Shandong 266003, P.R. China.
Chunting ZhaoDepartment of Hematology, The Affiliated Hospital of Qingdao University, Qingdao, Shandong 266003, P.R. China.
Xiaodan LiuDepartment of Hematology, The Affiliated Hospital of Qingdao University, Qingdao, Shandong 266003, P.R. China.
Affiliated Hospital of Qingdao University · CNQingdao University · CNJining First People's Hospital · CNPeople’s Hospital of Rizhao · CNWeifang Chinese Medicine Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The current study aimed to explore the levels of leptin (LEP) and LEP receptor (LEP-R) on the progression of aplastic anemia (AA) with bone marrow fat conversion. An AA model was developed by infusing C57BL/6 lymph node cells into BALB/c mice. At 0, 3, 6, 9, 12, 15 and 18 days after modeling, routine blood counts, bone marrow biopsy slides, lymphocyte subsets (CD4

Indexed as

aplastic anemialeptinleptin receptormesenchymal stem cells

Identifiers

PMID31316601
PMCPMC6601404
OpenAlexW2951998772

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.