ArticleFrontiers in genetics2019
Single-Locus and Multi-Locus Genome-Wide Association Studies for Intramuscular Fat in Duroc Pigs.
Article in Frontiers in genetics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 1 of them a synthesis that pooled it.
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Who cites it
45 citing papers in PubMed, 1 synthesis or guideline pooled it, 101 citations in OpenAlex.
- Multi-ancestry genome-wide association meta-analysis identifies candidate genes for computed tomography-based carcass composition traits in pigs.Genetics, selection, evolution : GSE · 2025Pooled it
- The influence of structural variants from 2445 pigs on gene expression and complex traits.Nature communications · 2026Article
- Gene expression profiling by RNA-sequencing reveals regulators of intramuscular fat in Black Slavonian pigs.Scientific reports · 2026Article
- Candidate genes related to growth and milk production in three Anatolian goats revealed by GWAS.Mammalian genome : official journal of the International Mammalian Genome Society · 2026Article
- MicroRNA transcriptome analysis reveals the potential role of miRNAs in regulating adipocyte hyperplasia and hypertrophy.Frontiers in genetics · 2026Article
- An updated Pig Haplotype Reference Panel (PHARP 4.0) comprising 13,298 haplotypes.Communications biology · 2025Article
- Identification and Pathway Analysis of SNP Loci Affecting Abdominal Fat Deposition in Broilers.Animals : an open access journal from MDPI · 2025Article
- Transcriptome analysis reveals key genes and regulatory networks underlying intramuscular fat deposition in rabbits.BMC genomics · 2025Article
- Identification of Key Genes Related to Intramuscular Fat Content of Psoas Major Muscle in Saba Pigs by Integrating Bioinformatics and Machine Learning Based on Transcriptome Data.Animals : an open access journal from MDPI · 2025Article
- Validation of Polymorphisms Associated with the Immune Response After Vaccination Against Porcine Reproductive and Respiratory Syndrome Virus in Yorkshire Gilts.Veterinary sciences · 2025Article
- The effects of runs-of-homozygosity on pig domestication and breeding.BMC genomics · 2025Article
- Genome-wide association study of copy number variation and early growth traits in inner Mongolian cashmere goats.Frontiers in veterinary science · 2025Article
- A Single-Cell Atlas of Porcine Skeletal Muscle Reveals Mechanisms That Regulate Intramuscular Adipogenesis.International journal of molecular sciences · 2024Article
- Genome-wide association studies of body size traits in Tibetan sheep.BMC genomics · 2024Article
- Genome-Wide Association Study for Weight Loss at the End of Dry-Curing of Hams Produced from Purebred Heavy Pigs.Animals : an open access journal from MDPI · 2024Article
- Identification and characterization of structural variants related to meat quality in pigs using chromosome-level genome assemblies.BMC genomics · 2024Article
- Performance, carcass quality and meat quality of the endangered German Angler Saddleback pig.PloS one · 2024Article
- Selective Sweeps in the Austrian Turopolje and Other Commercial Pig Populations.Animals : an open access journal from MDPI · 2023Article
- Genome-wide unraveling SNP pairwise epistatic effects associated with sheep body weight.Animal biotechnology · 2023Article
- Genome-wide association analysis unveils candidate genes and loci associated with aplasia cutis congenita in pigs.BMC genomics · 2023Article
Corrections and comments
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Authors and funding
13 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Intramuscular fat (IMF) is an important quantitative trait of meat, which affects the associated sensory properties and nutritional value of pork. To gain a better understanding of the genetic determinants of IMF, we used a composite strategy, including single-locus and multi-locus association analyses to perform genome-wide association studies (GWAS) for IMF in 1,490 Duroc boars. We estimated the genomic heritability of IMF to be 0.23 ± 0.04. A total of 30 single nucleotide polymorphisms (SNPs) were found to be significantly associated with IMF. The single-locus mixed linear model (MLM) and multiple-locus methods multi-locus random-SNP-effect mixed linear model (mrMLM), fast multi-locus random-SNP-effect efficient mixed model association (FASTmrEMMA), and integrative sure independence screening expectation maximization Bayesian least absolute shrinkage and selection operator model (ISIS EM-BLASSO) analyses identified 5, 9, 8, and 21 significant SNPs, respectively. Interestingly, a novel quantitative trait locus (QTL) on SSC 7 was found to affect IMF. In addition, 10 candidate genes (
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