Evidence map›Paper›PMID 31316384›Full record

ArticleFrontiers in pharmacology2019

Recovery of Sesamin, Sesamolin, and Minor Lignans From Sesame Oil Using Solid Support-Free Liquid-Liquid Extraction and Chromatography Techniques and Evaluation of Their Enzymatic Inhibition Properties.

Dimitris Michailidis, Apostolis Angelis, Nektarios Aligiannis, Sofia Mitakou, Léandros Skaltsounis

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
7.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 42 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Sesame Seeds: A Nutrient-Rich Superfood.Foods (Basel, Switzerland) · 2024
    Review
  6. Review
  7. Identification of Sesamin fromMolecules (Basel, Switzerland) · 2023
    Article
  8. Article
  9. Review
  10. Review
  11. A New Xanthone Glycoside fromMolecules (Basel, Switzerland) · 2022
    Article
  12. Article
  13. Review
  14. Plants (Basel, Switzerland) · 2021
    Article
  15. Article
  16. Lignans of Sesame (Molecules (Basel, Switzerland) · 2021
    Review
  17. Exploitation ofMolecules (Basel, Switzerland) · 2021
    Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Dimitris MichailidisFaculty of Pharmacy, Department of Pharmacognosy and Natural Products Chemistry, University of Athens, Athens, Greece.
Apostolis AngelisFaculty of Pharmacy, Department of Pharmacognosy and Natural Products Chemistry, University of Athens, Athens, Greece.
Nektarios AligiannisFaculty of Pharmacy, Department of Pharmacognosy and Natural Products Chemistry, University of Athens, Athens, Greece.
Sofia MitakouFaculty of Pharmacy, Department of Pharmacognosy and Natural Products Chemistry, University of Athens, Athens, Greece.
Léandros SkaltsounisFaculty of Pharmacy, Department of Pharmacognosy and Natural Products Chemistry, University of Athens, Athens, Greece.
National and Kapodistrian University of Athens · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this study, an integrated process for the recovery of sesamin and sesamolin, two high added-value lignans of sesame oil (SO) was developed, using synchronous extraction and chromatography techniques. The extraction of SO phenolic content was studied using two different extraction techniques: Annular centrifugal extraction (ACE) and centrifugal partition extraction (CPE). The derived data of each experiment were compared in terms of revealing the yields, time, and solvents consumption showing that CPE is the most effective technique, concerning the solvent consumption. The isolation of lignans was achieved using centrifugal partition chromatography (CPC) both on semi-preparative and preparative scale. The biphasic system used for this purpose consisted of the following solvents: n-Hex/EtOAc/EtOH/H

Indexed as

annular centrifugal extractioncentrifugal partition chromatographycentrifugal partition extractioncollagenase inhibition activityliquid–liquid extractionsesame oilsesaminsesamolin

Identifiers

PMID31316384
PMCPMC6610769
OpenAlexW2954898999

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.