Evidence map›Paper›PMID 31316159›Full record

ArticleEye (London, England)2019

Optical coherence tomography angiography findings in preeclampsia.

Emine Ciloglu, Nefise Tanrıdan Okcu, Neşe Çetin Dogan

Open access · bronzeAbstract readComparative Study
In one paragraph

Article in Eye (London, England), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.

  1. Retinal imaging in pre-eclamptic pregnancy: systematic review.Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology · 2026
    Pooled it
  2. Article
  3. Article
  4. Review
  5. Correlation of Ocular Plane-Wave Doppler With Optical Coherence Tomography Angiography in Preeclampsia.Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine · 2023
    Article
  6. Placental syndromes and long-term risk of hypertension.Journal of human hypertension · 2023
    Review
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Plane-Wave Ultrasound Doppler of the Eye in Preeclampsia.Translational vision science & technology · 2020
    Article
  13. Article
  14. Evaluation of the Choroid in Women with Uncomplicated Pregnancy.Translational vision science & technology · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Emine CilogluDepartment of Ophthalmology, Adana City Training and Research Hospital, Adana, Turkey. drciloglu@gmail.com.ORCID http://orcid.org/0000-0002-1266-3333
Nefise Tanrıdan OkcuDepartment of Obstetrics and Gynaecology, Adana City Training and Research Hospital, Adana, Turkey.
Neşe Çetin DoganDepartment of Ophthalmology, Adana City Training and Research Hospital, Adana, Turkey.ORCID http://orcid.org/0000-0001-8836-1588

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo investigate vascular density analysis in the superficial (SCP) and deep capillary plexus (DCP), foveal avascular zone (FAZ), peripapillary vascular density analysis (PPCVD), and peripapillary retinal nerve fiber thickness analysis (PPRNFL) using optical coherence tomography angiography (OCTA) in pregnant women with preeclampsia and to compare the obtained values with healthy pregnant and nonpregnant healthy individuals.

methodsA total of 98 pregnant women (55 had preeclampsia, 43 were healthy pregnant women) and 38 healthy nonpregnant women of reproductive age were included in the study. The patients were divided into three groups. Group 1 consisted of pregnant women with preeclampsia, group 2 comprised healthy pregnant women without preeclampsia, and group 3 consisted of healthy women who were not pregnant. All participants underwent a comprehensive ophthalmologic examination including OCTA.

resultsSuperficial foveal density (SFD) and deep foveal density (DFD) were lower in group 1 than in group 3 (p = 0.033, p = 0.041, respectively). Deep parafoveal density (DPD), deep temporal density (DTD), and deep superior density (DSD) values were lower in group 1 than in group 2 and group 3 (p = 0.001). PPRNFL superior and mean values were higher in group 1 and group 2 than in group 3 (p = 0.022, p = 0.029, respectively). The mean superior and inferior RPCVD values were significantly higher in group 1 than in group 2 and group 3 (p = 0.001, p = 0.043, and p = 0.001, respectively).

conclusionsIn preeclampsia, OCTA shows changes in the microvascular structure of the retina, even without retinopathy findings on biomicroscopy examination.

Indexed as

AdultCapillariesCase-Control StudiesFemaleFluorescein AngiographyFollow-Up StudiesFovea CentralisFundus OculiHumansPre-EclampsiaPregnancyProspective StudiesRetinal DiseasesRetinal VesselsTomography, Optical Coherence

Identifiers

PMID31316159
PMCPMC7002503
OpenAlexW2956505506

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.