Evidence map›Paper›PMID 31316103›Full record

ArticleScientific reports2019

A Naturally Occurring Splice Variant of GGA1 Inhibits the Anterograde Post-Golgi Traffic of α

Maoxiang Zhang, Xin Xu, Chunman Li, Wei Huang, Nenggui Xu, Guangyu Wu

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Maoxiang ZhangSouth China Research Center for Acupuncture and Moxibustion, Guangzhou University of Chinese Medicine, Guangzhou, 510006, China.
Xin XuDepartment of Pharmacology and Toxicology, Medical College of Georgia, Augusta University, Augusta, GA, 30912, USA.
Chunman LiDepartment of Pharmacology and Toxicology, Medical College of Georgia, Augusta University, Augusta, GA, 30912, USA.
Wei HuangDepartment of Pharmacology and Toxicology, Medical College of Georgia, Augusta University, Augusta, GA, 30912, USA.
Nenggui XuSouth China Research Center for Acupuncture and Moxibustion, Guangzhou University of Chinese Medicine, Guangzhou, 510006, China.
Guangyu WuDepartment of Pharmacology and Toxicology, Medical College of Georgia, Augusta University, Augusta, GA, 30912, USA. guwu@augusta.edu.
Augusta University · USGuangzhou University of Chinese Medicine · CN

Funding

Anterograde transport and signal regulation of GPCRsR01GM118915 · NIGMS · AUGUSTA UNIVERSITY · PI WU, GUANGYU · 2016 to 2019
$1.3M
NIGMS NIH HHS R01 GM118915
6 · The paper itself

Abstract

The regulatory mechanisms of cell surface targeting of nascent G protein-coupled receptors (GPCRs) en route from the endoplasmic reticulum through the Golgi remain poorly understood. We have recently demonstrated that three Golgi-localized, γ-adaptin ear domain homology, ADP ribosylation factor-binding proteins (GGAs) mediate the post-Golgi export of α

Indexed as

Adaptor Proteins, Vesicular TransportADP-Ribosylation FactorsAlternative SplicingCarrier ProteinsCell LineClathrinDimerizationEndoplasmic ReticulumGolgi ApparatusHEK293 CellsHeLa CellsHumansProtein BindingProtein Structure, TertiaryProtein TransportReceptors, Adrenergic, alpha-2Adaptor Proteins, Vesicular TransportADP-Ribosylation FactorsCarrier ProteinsClathrinGGA adaptor proteinsReceptors, Adrenergic, alpha-2Receptors, G-Protein-Coupled

Identifiers

PMID31316103
PMCPMC6637153
OpenAlexW2960207552

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.