Evidence map›Paper›PMID 31315989›Full record

ArticleJournal of virology2019

Evidence for Internal Initiation of RNA Synthesis by the Hepatitis C Virus RNA-Dependent RNA Polymerase NS5B

Philipp Schult, Maren Nattermann, Chris Lauber, Stefan Seitz, Volker Lohmann

Open access · bronzeAbstract read
In one paragraph

Article in Journal of virology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Philipp SchultDepartment for Infectious Diseases, Molecular Virology, University of Heidelberg, Heidelberg, Germany.
Maren NattermannDepartment for Infectious Diseases, Molecular Virology, University of Heidelberg, Heidelberg, Germany.
Chris LauberGerman Cancer Research Center (DKFZ), Division Virus-Associated Carcinogenesis (F170), Heidelberg, Germany.
Stefan SeitzDepartment for Infectious Diseases, Molecular Virology, University of Heidelberg, Heidelberg, Germany.
Volker LohmannDepartment for Infectious Diseases, Molecular Virology, University of Heidelberg, Heidelberg, Germany volker.lohmann@med.uni-heidelberg.de.ORCID 0000-0001-8719-7608
Heidelberg University · DEGerman Cancer Research Center · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Initiation of RNA synthesis by the hepatitis C virus (HCV) RNA-dependent RNA polymerase (RdRp) NS5B has been extensively studied

Indexed as

Transcription Initiation, GeneticVirus ReplicationCell LineGene Expression ProfilingHepacivirusHumansRNA-Dependent RNA PolymeraseRNA, ViralViral Nonstructural ProteinsNS-5 protein, hepatitis C virusRNA-Dependent RNA PolymeraseRNA, ViralViral Nonstructural Proteinsflaviviridaehepatitis C virusinitiationNS5Bpositive-strand RNA virusRdRpRNA-dependent RNA polymeraseRNA polymerasesRNA synthesissubgenomic RNA

Identifiers

PMID31315989
PMCPMC6744235
OpenAlexW2960157012

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.