Evidence map›Paper›PMID 31315957›Full record

ArticleJournal of clinical microbiology2019

Point-Counterpoint: Differences between the European Committee on Antimicrobial Susceptibility Testing and Clinical and Laboratory Standards Institute Recommendations for Reporting Antimicrobial Susceptibility Results.

Gunnar Kahlmeter, Christian G Giske, Thomas J Kirn, Susan E Sharp

Abstract readComparative Study
In one paragraph

Article in Journal of clinical microbiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
62citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

62 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Metronidazole Susceptibility Patterns in EuropeanMedical sciences (Basel, Switzerland) · 2026
    Pooled it
  2. Safety Evaluation ofFood science & nutrition · 2026
    Article
  3. Article
  4. Performance evaluation of antimicrobial susceptibility testing methods for ceftazidime-avibactam and imipenem-relebactam against Klebsiella pneumoniae and Pseudomonas aeruginosa.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026
    Article
  5. Review
  6. Pathogens (Basel, Switzerland) · 2026
    Article
  7. Article
  8. Article
  9. Occurrence ofMicroorganisms · 2025
    Article
  10. Article
  11. Antimicrobial Susceptibility ofMicroorganisms · 2025
    Article
  12. ClinicalOpen veterinary journal · 2025
    Article
  13. Biological characterization of novelFrontiers in microbiology · 2025
    Article
  14. Article
  15. Antimicrobial Resistance ofAntibiotics (Basel, Switzerland) · 2024
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article

2 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Gunnar KahlmeterEUCAST Steering Committee.
Christian G GiskeEUCAST Steering Committee christian.giske@eucast.org kirntj@rwjms.rutgers.edu.
Thomas J KirnRutgers Robert Wood Johnson Medical School, New Brunswick, New Jersey, USA christian.giske@eucast.org kirntj@rwjms.rutgers.edu.
Susan E SharpCopan Diagnostics, Inc., Murrieta, California, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

INTRODUCTIONAntibiotic susceptibility test results are among the most important results issued by clinical microbiology laboratories because they routinely guide critical treatment decisions. Interpretations of MIC or disk diffusion test results, such as "susceptible" or "resistant," are easily understood. Clinical laboratories also need to determine whether and how their reports will reflect more complex situations. Such situations include, first, whether there is need to administer higher or more frequent doses of antibiotic than usual for clinical efficacy; second, whether an antimicrobial is likely to be effective at a body site where it concentrates; and third, whether there is some uncertainty in the test results due to technical variability that cannot be eliminated. Two leading organizations that set standards for antimicrobial susceptibility testing, the European Committee on Antimicrobial Susceptibility Testing (EUCAST) and the Clinical and Laboratory Standards Institute (CLSI), have taken different strategies to deal with these challenges. In this Point-Counterpoint, Gunnar Kahlmeter and Christian Giske discuss how EUCAST is addressing these issues, and Thomas Kirn and Susan Sharp discuss the CLSI approach.

Indexed as

Anti-Bacterial AgentsBacteriaHumansMicrobial Sensitivity TestsResearch DesignAnti-Bacterial Agentsantimicrobial agentssusceptibility testing

Identifiers

PMID31315957
PMCPMC6711922

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.