Evidence map›Paper›PMID 31315951›Full record

ArticleJournal of clinical microbiology2019

Molecular Diagnosis of Vaginitis: Comparing Quantitative PCR and Microbiome Profiling Approaches to Current Microscopy Scoring.

Tarah Lynch, Gisele Peirano, Tracie Lloyd, Ron Read, Julia Carter, Angel Chu, Jeffrey A Shaman, Joseph P Jarvis, Evan Diamond, Umer Zeeshan Ijaz and 1 more

Open access · bronzeAbstract readComparative StudyEvaluation Study
In one paragraph

Article in Journal of clinical microbiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 2 pooled it
2.2field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 2 syntheses or guidelines pooled it, 30 citations in OpenAlex.

  1. Pooled it
  2. The Role of Genital Tract Microbiome in Fertility: A Systematic Review.International journal of molecular sciences · 2021
    Pooled it
  3. Article
  4. Review
  5. Management of Recurrent Vaginitis.Current obstetrics and gynecology reports · 2026
    Review
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 3 countries.

Tarah LynchDepartment of Pathology & Laboratory Medicine, University of Calgary, Calgary, Alberta, Canada tarah.lynch@ahs.ca.
Gisele PeiranoDivision of Microbiology, Calgary Laboratory Services, Calgary, Alberta, Canada.
Tracie LloydDivision of Microbiology, Calgary Laboratory Services, Calgary, Alberta, Canada.
Ron ReadDepartment of Medicine, University of Calgary, Calgary, Alberta, Canada.
Julia CarterSexual and Reproductive Health, Alberta Health Services, Calgary, Alberta, Canada.
Angel ChuDepartment of Medicine, University of Calgary, Calgary, Alberta, Canada.
Jeffrey A ShamanCoriell Life Sciences, Philadelphia, Pennsylvania, USA.
Joseph P JarvisCoriell Life Sciences, Philadelphia, Pennsylvania, USA.
Evan DiamondThermo Fisher Scientific, San Francisco, California, USA.
Umer Zeeshan IjazSchool of Engineering, Oakfield Avenue, University of Glasgow, Glasgow, United Kingdom.
Deirdre ChurchDepartment of Pathology & Laboratory Medicine, University of Calgary, Calgary, Alberta, Canada.
Calgary Laboratory Services · CAAlberta Health Services · CACoriell Institute For Medical Research · USThermo Fisher Scientific (United States) · USUniversity of Calgary · CAUniversity of Glasgow · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vaginitis is often diagnosed by microscopy and limited to testing for bacterial vaginosis (BV), vulvovaginal candidiasis, and trichomoniasis. Approximately 10% of vaginal swabs are negative but designated "altered flora" by BV Nugent score, leaving clinicians unsure how to treat patients. Accurate and comprehensive vaginitis diagnostics are needed to direct treatment and reduce risks of recurrent or more severe infections. Vaginal swabs were collected from 93 women (mean age, 23.53 years; range, 18 to 42 years) in a cross-sectional study. Microscopy results for BV and

Indexed as

AdolescentAdultCandidiasis, VulvovaginalCross-Sectional StudiesDiagnostic Tests, RoutineFemaleHumansMicroscopyReal-Time Polymerase Chain ReactionVaginaVaginosis, BacterialYoung Adult16s rRNA geneaerobic vaginitisbacterial vaginosisdysbiosismicrobiomemicroscopymolecular diagnosticsNugent scoreqPCR

Identifiers

PMID31315951
PMCPMC6711928
OpenAlexW2960603005

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.