Evidence map›Paper›PMID 31315950›Full record

ArticleJournal of clinical microbiology2019

Clostridioides difficile Whole-Genome Sequencing Reveals Limited Within-Host Genetic Diversity in a Pediatric Cohort.

Aakash Balaji, Egon A Ozer, Larry K Kociolek

Open access · bronzeAbstract read
In one paragraph

Article in Journal of clinical microbiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Open forum infectious diseases · 2026
    Article
  2. Phenotypic analysis of variousApplied and environmental microbiology · 2025
    Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Aakash BalajiDepartment of Pediatrics, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
Egon A OzerDepartment of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.ORCID 0000-0002-7131-3691
Larry K KociolekDepartment of Pediatrics, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA larry-kociolek@northwestern.edu.
Northwestern University · US

Funding

Northwestern University Clinical and Translational Science Institute (NUCATS)UL1TR001422 · NCATS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI D'AQUILA, RICHARD · 2015 to 2023
$56.8M
Optimizing the diagnosis of pediatric Clostridium difficile infectionK23AI123525 · NIAID · LURIE CHILDREN'S HOSPITAL OF CHICAGO · PI KOCIOLEK, LARRY K · 2016 to 2020
$937k
NCATS NIH HHS UL1 TR001422NIAID NIH HHS K23 AI123525
6 · The paper itself

Abstract

Whole-genome sequencing (WGS) is a highly sensitive method for identifying genetic relatedness and transmission of

Indexed as

Genetic VariationWhole Genome SequencingCarrier StateChildChild, PreschoolClostridioides difficileClostridium InfectionsCohort StudiesFecesFemaleHumansInfantMaleClostridium difficilegenomicspediatricstransmissionwhole-genome sequencing

Identifiers

PMID31315950
PMCPMC6711918
OpenAlexW2962655745

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.