Evidence map›Paper›PMID 31315266›Full record

ArticleJournal of clinical medicine2019

Electrospun Polyethylene Terephthalate Nanofibers Loaded with Silver Nanoparticles: Novel Approach in Anti-Infective Therapy.

Alexandru Mihai Grumezescu, Alexandra Elena Stoica, Mihnea-Ștefan Dima-Bălcescu, Cristina Chircov, Sami Gharbia, Cornel Baltă, Marcel Roșu, Hildegard Herman, Alina Maria Holban, Anton Ficai and 4 more

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 59 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 1 country.

Alexandru Mihai GrumezescuDepartment of Science and Engineering of Oxide Materials and Nanomaterials, Faculty of Applied Chemistry and Materials Science, University Politehnica of Bucharest, 060042 Bucharest, Romania.ORCID 0000-0003-3036-094X
Alexandra Elena StoicaDepartment of Science and Engineering of Oxide Materials and Nanomaterials, Faculty of Applied Chemistry and Materials Science, University Politehnica of Bucharest, 060042 Bucharest, Romania.
Mihnea-Ștefan Dima-BălcescuFaculty of Engineering in Foreign Languages, University Politehnica of Bucharest, 060042 Bucharest, Romania.
Cristina ChircovDepartment of Science and Engineering of Oxide Materials and Nanomaterials, Faculty of Applied Chemistry and Materials Science, University Politehnica of Bucharest, 060042 Bucharest, Romania.
Sami GharbiaInstitute of Life Sciences, Vasile Goldis Western University of Arad, 310414 Arad, Romania.
Cornel BaltăInstitute of Life Sciences, Vasile Goldis Western University of Arad, 310414 Arad, Romania.
Marcel RoșuInstitute of Life Sciences, Vasile Goldis Western University of Arad, 310414 Arad, Romania.
Hildegard HermanInstitute of Life Sciences, Vasile Goldis Western University of Arad, 310414 Arad, Romania.ORCID 0000-0002-6741-0245
Alina Maria HolbanDepartment of Science and Engineering of Oxide Materials and Nanomaterials, Faculty of Applied Chemistry and Materials Science, University Politehnica of Bucharest, 060042 Bucharest, Romania.
Anton FicaiDepartment of Science and Engineering of Oxide Materials and Nanomaterials, Faculty of Applied Chemistry and Materials Science, University Politehnica of Bucharest, 060042 Bucharest, Romania.
Bogdan Stefan VasileDepartment of Science and Engineering of Oxide Materials and Nanomaterials, Faculty of Applied Chemistry and Materials Science, University Politehnica of Bucharest, 060042 Bucharest, Romania.ORCID 0000-0002-2267-6453
Ecaterina AndronescuDepartment of Science and Engineering of Oxide Materials and Nanomaterials, Faculty of Applied Chemistry and Materials Science, University Politehnica of Bucharest, 060042 Bucharest, Romania. ecaterina.andronescu@upb.ro.
Mariana Carmen ChifiriucICUB, Research Institute of Bucharest University, University of Bucharest, 030018 Bucharest, Romania.
Anca HermeneanDepartment of Science and Engineering of Oxide Materials and Nanomaterials, Faculty of Applied Chemistry and Materials Science, University Politehnica of Bucharest, 060042 Bucharest, Romania.ORCID 0000-0001-8510-6653
Universitatea Națională de Știință și Tehnologie Politehnica București · ROVasile Goldis Western University of Arad · ROUniversity of Bucharest · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Polyethylene terephthalate (PET) is a major pollutant polymer, due to its wide use in food packaging and fiber production industries worldwide. Currently, there is great interest for recycling the huge amount of PET-based materials, derived especially from the food and textile industries. In this study, we applied the electrospinning technique to obtain nanostructured fibrillary membranes based on PET materials. Subsequently, the recycled PET networks were decorated with silver nanoparticles through the chemical reduction method for antimicrobial applications. After the characterization of the materials in terms of crystallinity, chemical bonding, and morphology, the effect against Gram-positive and Gram-negative bacteria, as well as fungal strains, was investigated. Furthermore, in vitro and in vivo biocompatibility tests were performed in order to open up potential biomedical applications, such as wound dressings or implant coatings. Silver-decorated fibers showed lower cytotoxicity and inflammatory effects and increased antibiofilm activity, thus highlighting the potential of these systems for antimicrobial purposes.

Indexed as

antimicrobial agentsbiocompatibilityelectrospinningnanofibersPETpolyethylene terephthalatesilver nanoparticles

Identifiers

PMID31315266
PMCPMC6679131
OpenAlexW2956913114

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.