Evidence map›Paper›PMID 31315254›Full record

ArticleMedicina (Kaunas, Lithuania)2019

Use of Plasmapheresis and Immunosuppressants to Treat Diffuse Alveolar Hemorrhage in a Patient with Granulomatosis with Polyangiitis.

Yasar Sattar, Ammu Thampi Susheela, Waqas Ullah, Norina Usman, Fnu Zafrullah

Open access · goldAbstract readCase Reports
In one paragraph

Article in Medicina (Kaunas, Lithuania), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Yasar SattarIcahn School of Medicine at Mount Sinai-Elmhurst Hospital, Queens, NY 11373, USA. sattary@nychhc.org.ORCID 0000-0002-1304-5748
Ammu Thampi SusheelaBeth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA.
Waqas UllahAbington Hospital Jefferson Health, Abington, PA 19001, USA.ORCID 0000-0002-4850-0309
Norina UsmanLasante Health Clinic, Brooklyn, NY 11226, USA.
Fnu ZafrullahSteward Carney Hospital, Tufts Medical Center, Boston, MA 02111, USA.
Abington Memorial Hospital · USBeth Israel Deaconess Medical Center · USElmhurst Hospital Center · USTufts Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Granulomatosis with polyangiitis (GPA) is a systemic granulomatous inflammatory disease characterized by small-to-medium vessel vasculitis due to Central Anti-Neutrophil Cytoplasmic Antibody (C-ANCA). GPA commonly involves the lungs and the kidneys. Among the pulmonary manifestations, diffuse alveolar hemorrhage (DHA) is a rare presentation of GPA that can present with hemoptysis leading to acute onset of anemia and hemodynamic instability. An active diagnostic workup including serologic titer of C-ANCA, imaging, intensive care, and aggressive immunosuppression is the key to DAH management. We report a case of DAH secondary to GPA that presented with hemoptysis leading to severe anemia, initially resuscitated symptomatically and started on plasmapheresis with pulse steroids and cyclophosphamide. Timely diagnosis and management led to a remarkable recovery of the pulmonary symptoms and imaging findings of DAH.

Indexed as

Antibodies, Antineutrophil CytoplasmicBiomarkersEmergency Service, HospitalFemaleGranulomatosis with PolyangiitisHumansImmunosuppressive AgentsMiddle AgedPlasmapheresisRadiographyAntibodies, Antineutrophil CytoplasmicBiomarkersImmunosuppressive Agentscyclophosphamidediffuse alveolar hemorrhagegranulomatosis with polyangiitisplasmapheresisprednisonerituximab

Identifiers

PMID31315254
PMCPMC6681500
OpenAlexW2956534477

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.