ReviewJournal of clinical medicine2019
Changes in Spinal and Corticospinal Excitability in Patients with Chronic Ankle Instability: A Systematic Review with Meta-Analysis.
Review in Journal of clinical medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06118879 (Role of Sensory Deficits and the Effect of Sensory Stimulation on Sensorimotor Control and Neuromuscular Performance in Athletes With Chronic Ankle Instability), which is not on this map. Cited by 26 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Role of Sensory Deficits and the Effect of Sensory Stimulation on Sensorimotor Control and Neuromuscular Performance in Athletes With Chronic Ankle Instability
Who cites it
26 citing papers in PubMed, 3 syntheses or guidelines pooled it, 59 citations in OpenAlex.
- Alterations in corticospinal excitability in individuals with ankle sprains: a systematic review of transcranial magnetic stimulation studies.Frontiers in physiology · 2026Pooled it
- Brain Neuroplasticity Related to Lateral Ankle Ligamentous Injuries: A Systematic Review.Sports medicine (Auckland, N.Z.) · 2023Pooled it
- Effects of plantar-sensory treatments on postural control in chronic ankle instability: A systematic review and meta-analysis.PloS one · 2023Pooled it
- Corticomotor Excitability Changes Induced by Progressive Balance Exercises in Chronic Ankle Instability: a Randomized Clinical Trial.Brain and behavior · 2026Trial
- Multimodal pain management in foot and ankle surgery and trauma: a narrative review.Musculoskeletal surgery · 2026Review
- Injury prevention relevance: markerless functional performance testing in athletes with chronic ankle instability to inform recurrent sprain risk screening.BMC sports science, medicine & rehabilitation · 2026Article
- Increased common corticospinal input during eyes-closed unilateral stance in people with chronic ankle instability.Scientific reports · 2026Article
- Changes in the cortical GABAergic inhibitory system with ageing and ageing-related neurodegenerative diseases.The Journal of physiology · 2026Review
- Corticospinal tract alterations after ankle sprain in adolescence: Insights from the mouse model.Sports medicine and health science · 2025Article
- Article
- Effects of Acute Lateral Ankle Sprain on Spinal Reflex Excitability and Time-to-Boundary Postural Control in Single-Leg Stance.Healthcare (Basel, Switzerland) · 2025Article
- Patients with chronic ankle instability exhibit increased sensorimotor cortex, dorsolateral prefrontal cortex, and superior temporal gyrus activation during single-leg stance: a functional near-infrared spectroscopy study.Frontiers in human neuroscience · 2025Article
- Neural-Targeted Rehabilitation Strategies to Address Neuroplasticity After Joint Injury.Journal of athletic training · 2024Review
- Impact of subtalar joint mobilization on walking ability in patients with intra-articular varus of the hindfoot joint with chronic ankle instability.Journal of orthopaedic surgery and research · 2024Article
- Soleus arthrogenic muscle inhibition following acute lateral ankle sprain correlates with symptoms and ankle disability but not with postural control.Journal of sport and health science · 2024Article
- Patients with chronic ankle instability exhibit increased sensorimotor cortex activation and correlation with poorer lateral balance control ability during single-leg stance: a FNIRS study.Frontiers in human neuroscience · 2024Article
- Test-retest, intra- and inter-rater reliability of the reactive balance test in patients with chronic ankle instability.Frontiers in neurology · 2024Article
- Case report: High-frequency repetitive transcranial magnetic stimulation for treatment of hereditary spastic paraplegia type 11.Frontiers in neurology · 2023Article
- Conduction Velocity of Spinal Reflex in Patients with Acute Lateral Ankle Sprain.Healthcare (Basel, Switzerland) · 2022Article
- Spinal Reflex Excitability of Lower Leg Muscles Following Acute Lateral Ankle Sprain: Bilateral Inhibition of Soleus Spinal Reflex Excitability.Healthcare (Basel, Switzerland) · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The objective of this systematic review with meta-analysis was to determine alterations in spinal and corticospinal excitability of ankle muscles in patients with chronic ankle instability (CAI) compared to uninjured controls. Independent researchers performed comprehensive literature searches of electronic databases and included studies that compared groups with and without CAI and investigated neural excitability with Hoffmann reflex (H-reflex) and/or transcranial magnetic stimulation (TMS). A fixed-effect meta-analysis was conducted to determine group differences for (1) soleus and fibularis maximal H-reflex (Hmax)/maximal M-wave (Mmax)-ratios, and (2) soleus and fibularis longus cortical motor thresholds (CMTs). Seventeen studies were included in the current meta-analysis. They showed that the Hmax/Mmax-ratios of the soleus and the fibularis longus in the CAI group were significantly lower than those in the uninjured control group (soleus: d = -0.41,
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.