Evidence map›Paper›PMID 31315211›Full record

ArticleInternational journal of molecular sciences2019

Effects of Diazepam on Low-Frequency and High-Frequency Electrocortical γ-Power Mediated by α1- and α2-GABA

Julian I Hofmann, Cornelius Schwarz, Uwe Rudolph, Bernd Antkowiak

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Julian I HofmannWerner Reichardt Center for Integrative Neuroscience, Eberhard-Karls-University Tübingen, 72076 Tübingen, Germany.
Cornelius SchwarzWerner Reichardt Center for Integrative Neuroscience, Eberhard-Karls-University Tübingen, 72076 Tübingen, Germany.
Uwe RudolphDepartment of Comparative Biosciences, College of Veterinary Medicine, University of Illinois at Urbana-Champain, Urbana, IL 61802-6178 USA.ORCID 0000-0001-9396-4746
Bernd AntkowiakWerner Reichardt Center for Integrative Neuroscience, Eberhard-Karls-University Tübingen, 72076 Tübingen, Germany. bernd.antkowiak@uni-tuebingen.de.
University of Tübingen · DEUniversity of Illinois Urbana-Champaign · US

Funding

The Role of GABA A Receptor Subtypes in Benzodiazepine Abuse LiabilityR03DA033491 · NIDA · MCLEAN HOSPITAL · PI RUDOLPH, UWE · 2012 to 2013
$155k
Emotional regulation: Modeling GABA A receptor subtype specific agents in miceR03MH094834 · NIMH · MCLEAN HOSPITAL · PI RUDOLPH, UWE · 2012 to 2013
$155k
Deutsche Forschungsgemeinschaft AN321/2-1Deutsche Forschungsgemeinschaft SCHW577/8-1NIDA NIH HHS R03 DA033491NIDA NIH HHS R03DA033491NIMH NIH HHS R03 MH094834NIMH NIH HHS R03MH094834
6 · The paper itself

Abstract

Patterns of spontaneous electric activity in the cerebral cortex change upon administration of benzodiazepines. Here we are testing the hypothesis that the prototypical benzodiazepine, diazepam, affects spectral power density in the low (20-50 Hz) and high (50-90 Hz) γ-band by targeting GABA

Indexed as

Gamma RhythmAnimalsCerebral CortexCortical SynchronizationDiazepamGABA ModulatorsMaleMiceMutationReceptors, GABA-ADiazepamGABA ModulatorsReceptors, GABA-Aaminobutyric acid(A) receptorsbenzodiazepineelectroencephalogramGABA(A)-receptor subtypesgamma-powerhypnotic

Identifiers

PMID31315211
PMCPMC6678188
OpenAlexW2957978555

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.