Evidence map›Paper›PMID 31315207›Full record

ReviewMicromachines2019

In Vivo Tracking of Tissue Engineered Constructs.

Carmen J Gil, Martin L Tomov, Andrea S Theus, Alexander Cetnar, Morteza Mahmoudi, Vahid Serpooshan

Abstract readReview
In one paragraph

Review in Micromachines, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

  1. Article
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  5. Article
  6. Image-Guided Cardiac Regeneration via a 3D Bioprinted Vascular Patch with Built-in CT Visibility.Chemical engineering journal (Lausanne, Switzerland : 1996) · 2025
    Article
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  14. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Carmen J GilWallace H. Coulter Department of Biomedical Engineering, Emory University School of Medicine and Georgia Institute of Technology, Atlanta, GA 30322, USA.ORCID 0000-0002-7113-2735
Martin L TomovWallace H. Coulter Department of Biomedical Engineering, Emory University School of Medicine and Georgia Institute of Technology, Atlanta, GA 30322, USA.
Andrea S TheusWallace H. Coulter Department of Biomedical Engineering, Emory University School of Medicine and Georgia Institute of Technology, Atlanta, GA 30322, USA.
Alexander CetnarWallace H. Coulter Department of Biomedical Engineering, Emory University School of Medicine and Georgia Institute of Technology, Atlanta, GA 30322, USA.
Morteza MahmoudiPrecision Health Program, Michigan State University, East Lansing, MI 48824, USA.ORCID 0000-0002-2575-9684
Vahid SerpooshanWallace H. Coulter Department of Biomedical Engineering, Emory University School of Medicine and Georgia Institute of Technology, Atlanta, GA 30322, USA. vahid.serpooshan@bme.gatech.edu.ORCID 0000-0002-5304-095X

Funding

Molecular and Cellular Mechanisms of Neonatal Cardiac Development and RepairR00HL127295 · NHLBI · EMORY UNIVERSITY · PI SERPOOSHAN, VAHID · 2018 to 2020
$729k
Foundation for the National Institutes of Health R00HL127295-04NHLBI NIH HHS R00 HL127295
6 · The paper itself

Abstract

To date, the fields of biomaterials science and tissue engineering have shown great promise in creating bioartificial tissues and organs for use in a variety of regenerative medicine applications. With the emergence of new technologies such as additive biomanufacturing and 3D bioprinting, increasingly complex tissue constructs are being fabricated to fulfill the desired patient-specific requirements. Fundamental to the further advancement of this field is the design and development of imaging modalities that can enable visualization of the bioengineered constructs following implantation, at adequate spatial and temporal resolution and high penetration depths. These in vivo tracking techniques should introduce minimum toxicity, disruption, and destruction to treated tissues, while generating clinically relevant signal-to-noise ratios. This article reviews the imaging techniques that are currently being adopted in both research and clinical studies to track tissue engineering scaffolds in vivo, with special attention to 3D bioprinted tissue constructs.

Indexed as

3D bioprintingadditive manufacturingbioluminescencecomputed tomography (CT)fluorescence spectroscopyin vivo imagingmagnetic-particle imagingmagnetic resonant imaging (MRI)multimodal imagingoptical coherence tomographyphotoacoustic imagingscaffold trackingtissue engineeringultrasound

Identifiers

PMID31315207
PMCPMC6680880

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.