Evidence map›Paper›PMID 31314709›Full record

ArticleVector borne and zoonotic diseases (Larchmont, N.Y.)2019

A Large Cohort of Neurocysticercosis in Shandong Province, Eastern China, 1997-2015.

Xiaodan Huang, Zhonglei Wang, Jingxuan Kou, Hongmei Liu, Dehua Mao, Zhenhua Yu, Xin Liu, Peng Cheng, Maoqing Gong

Registry-linked trialAbstract read
In one paragraph

Article in Vector borne and zoonotic diseases (Larchmont, N.Y.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04706819 (Clinical, Laboratory and Imaging Features, Treatment Trends and Long Term Outcomes in Patients With Parenchymal and Extraparenchymal Neurocysticercosis-A Registry Based Study), which is not on this map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04706819 unknown statusnot on this mapstarted 2021, after this paper: background citation

Clinical, Laboratory and Imaging Features, Treatment Trends and Long Term Outcomes in Patients With Parenchymal and Extraparenchymal Neurocysticercosis-A Registry Based Study

Typeobservational_patient_registrySponsorAll India Institute of Medical SciencesRan2021 to 2025Enrolled1,000ConditionsNeurocysticercosis, Tropical Disease, Tenia Solium Infection
3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Xiaodan HuangWorld Health Organization Collaborating Centre for Lymphatic Filariasis and Taeniasis/Cysticercosis, Shandong Institute of Parasitic Diseases, Shandong First Medical University & Shandong Academy of Medical Sciences, Jining, Shandong Province, China.
Zhonglei WangWorld Health Organization Collaborating Centre for Lymphatic Filariasis and Taeniasis/Cysticercosis, Shandong Institute of Parasitic Diseases, Shandong First Medical University & Shandong Academy of Medical Sciences, Jining, Shandong Province, China.
Jingxuan KouWorld Health Organization Collaborating Centre for Lymphatic Filariasis and Taeniasis/Cysticercosis, Shandong Institute of Parasitic Diseases, Shandong First Medical University & Shandong Academy of Medical Sciences, Jining, Shandong Province, China.
Hongmei LiuWorld Health Organization Collaborating Centre for Lymphatic Filariasis and Taeniasis/Cysticercosis, Shandong Institute of Parasitic Diseases, Shandong First Medical University & Shandong Academy of Medical Sciences, Jining, Shandong Province, China.
Dehua MaoWorld Health Organization Collaborating Centre for Lymphatic Filariasis and Taeniasis/Cysticercosis, Shandong Institute of Parasitic Diseases, Shandong First Medical University & Shandong Academy of Medical Sciences, Jining, Shandong Province, China.
Zhenhua YuWorld Health Organization Collaborating Centre for Lymphatic Filariasis and Taeniasis/Cysticercosis, Shandong Institute of Parasitic Diseases, Shandong First Medical University & Shandong Academy of Medical Sciences, Jining, Shandong Province, China.
Xin LiuWorld Health Organization Collaborating Centre for Lymphatic Filariasis and Taeniasis/Cysticercosis, Shandong Institute of Parasitic Diseases, Shandong First Medical University & Shandong Academy of Medical Sciences, Jining, Shandong Province, China.
Peng ChengWorld Health Organization Collaborating Centre for Lymphatic Filariasis and Taeniasis/Cysticercosis, Shandong Institute of Parasitic Diseases, Shandong First Medical University & Shandong Academy of Medical Sciences, Jining, Shandong Province, China.
Maoqing GongWorld Health Organization Collaborating Centre for Lymphatic Filariasis and Taeniasis/Cysticercosis, Shandong Institute of Parasitic Diseases, Shandong First Medical University & Shandong Academy of Medical Sciences, Jining, Shandong Province, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neurocysticercosis (NCC) has a wide spectrum of neurologic and psychiatric manifestations, including epileptic seizures, high intracranial pressure, cognitive dysfunction, and meningoencephalitis. This study presents the clinical diagnosis of 2539 NCC patients in Shandong Province, Eastern China, from 1997 to 2015. The diagnosis was based primarily on clinical features, neuroimaging, immunology, and electroencephalogramy studies. In all age groups, seizures were found to be the most common manifestation, followed by headaches, memory loss, and limb numbness, and disability. After antiparasitic treatment, computed tomography and magnetic resonance imaging showed that most of the lesions had been completely absorbed in 2106 (82.95%) patients, most of the lesions had been absorbed and a small proportion was converted into calcifications in 433 (17.05%) cases. Indirect hemagglutination (IHA), enzyme-linked immunosorbent assay (ELISA), and circulating antigen (CAg) serum tests initially gave 76.45%, 86.37%, and 80.66% positive results, respectively. After antiparasitic therapy, the positive rates of the IHA, ELISA, and CAg tests were 74.77%, 84.70%, and 3.75%, respectively, showing no significant difference in antibody levels (

Indexed as

AdolescentAdultChildChild, PreschoolChinaCohort StudiesFemaleHumansInfantMaleMiddle AgedNeurocysticercosisRetrospective StudiesRural PopulationUrban PopulationYoung Adultalbendazoleand praziquantelclinical featuresdiagnosisneurocysticercosis

Identifiers

PMID31314709
PMCPMC6882449

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.