Evidence map›Paper›PMID 31314636›Full record

ArticleJournal of neurophysiology2019

Missing pieces of the Piezo1/Piezo2 baroreceptor hypothesis: an autonomic perspective.

Sean D Stocker, Alan F Sved, Michael C Andresen

Open access · bronzeAbstract read
In one paragraph

Article in Journal of neurophysiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 2 pooled it
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 2 syntheses or guidelines pooled it, 38 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Review
  5. Article
  6. Article
  7. Article
  8. Piezo ion channels: long-sought-after mechanosensors mediating hypertension and hypertensive nephropathy.Hypertension research : official journal of the Japanese Society of Hypertension · 2024
    Review
  9. Article
  10. Review
  11. The 2021 Nobel Prize in Medicine and its relevance to autonomic medicine-and other updates on recent autonomic research.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2021
    Article
  12. Article
  13. Neural Circuits of Interoception.Trends in neurosciences · 2021
    Review
  14. Tentonin 3 as a baroreceptor mechanosensor: not a stretch.The Journal of clinical investigation · 2020
    Article
  15. Review
  16. Force Sensing by Piezo Channels in Cardiovascular Health and Disease.Arteriosclerosis, thrombosis, and vascular biology · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Sean D StockerDepartment of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania.
Alan F SvedDepartment of Neuroscience, University of Pittsburgh, Pittsburgh, Pennsylvania.
Michael C AndresenDepartment of Physiology and Pharmacology, Oregon Health Sciences University, Portland, Oregon.
University of Pittsburgh · USOregon Health & Science University · US

Funding

Adverse Neurogenic Actions of Dietary SaltR01HL128388 · NHLBI · UNIVERSITY OF DELAWARE · PI FARQUHAR, WILLIAM B, STOCKER, SEAN D · 2016 to 2019
$2.6M
Brain NaCl-sensing in salt-sensitive hypertension.R01HL145875 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI STOCKER, SEAN D · 2019 to 2022
$2.2M
NHLBI NIH HHS R01 HL128388NHLBI NIH HHS R01 HL145875
6 · The paper itself

Abstract

Baroreceptors play a pivotal role in the regulation of blood pressure through moment to moment sensing of arterial blood pressure and providing information to the central nervous system to make autonomic adjustments to maintain appropriate tissue perfusion. A recent publication by Zeng and colleagues (Zeng WZ, Marshall KL, Min S, Daou I, Chapleau MW, Abboud FM, Liberles SD,

Indexed as

AnimalsAutonomic Nervous SystemBaroreflexBlood PressureHumansIon ChannelsPressoreceptorsIon ChannelsPIEZO1 protein, humanPIEZO2 protein, humanautonomicbaroreceptorbaroreflexblood pressurePiezo

Identifiers

PMID31314636
PMCPMC6766733
OpenAlexW2961947479

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.