Evidence map›Paper›PMID 31314486›Full record

ArticleACS nano2019

Catalytic Nanoassemblies Formed by Short Peptides Promote Highly Enantioselective Transfer Hydrogenation.

Martin A Dolan, Prem N Basa, Oleksii Zozulia, Zsófia Lengyel, René Lebl, Eric M Kohn, Sagar Bhattacharya, Ivan V Korendovych

Open access · greenAbstract read
In one paragraph

Article in ACS nano, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.0field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 32 citations in OpenAlex.

  1. Mechanisms and pathology of protein misfolding and aggregation.Nature reviews. Molecular cell biology · 2023
    Review
  2. Review
  3. Article
  4. Article
  5. Review
  6. Fluorinated peptide biomaterials.Peptide science (Hoboken, N.J.) · 2021
    Article
  7. Article
  8. Article
  9. Synergistic Interactions Are Prevalent in Catalytic Amyloids.Chembiochem : a European journal of chemical biology · 2020
    Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Martin A DolanDepartment of Chemistry , Syracuse University , 111 College Place , Syracuse , New York 13244 , United States.
Prem N BasaDepartment of Chemistry , Syracuse University , 111 College Place , Syracuse , New York 13244 , United States.
Oleksii ZozuliaDepartment of Chemistry , Syracuse University , 111 College Place , Syracuse , New York 13244 , United States.ORCID 0000-0003-3803-4225
Zsófia LengyelDepartment of Chemistry , Syracuse University , 111 College Place , Syracuse , New York 13244 , United States.
René LeblDepartment of Chemistry , Syracuse University , 111 College Place , Syracuse , New York 13244 , United States.
Eric M KohnDepartment of Chemistry , Syracuse University , 111 College Place , Syracuse , New York 13244 , United States.
Sagar BhattacharyaDepartment of Chemistry , Syracuse University , 111 College Place , Syracuse , New York 13244 , United States.
Ivan V KorendovychDepartment of Chemistry , Syracuse University , 111 College Place , Syracuse , New York 13244 , United States.ORCID 0000-0001-8144-783X
Syracuse University · US

Funding

Understanding Evolution of Protein Function Through Design.R35GM119634 · NIGMS · SYRACUSE UNIVERSITY · PI KORENDOVYCH, IVAN V · 2016 to 2025
$4.3M
NIGMS NIH HHS R35 GM119634
6 · The paper itself

Abstract

Self-assembly enables formation of incredibly diverse supramolecular structures with practically important functions from simple and inexpensive building blocks. Here, we show how a semirational, bottom-up approach to create emerging properties can be extended to a design of highly enantioselective catalytic nanoassemblies. The designed peptides comprising as few as two amino acid residues spontaneously self-assemble in the presence of metal ions to form supramolecular, vesicle-like nanoassemblies that promote transfer hydrogenation of ketones in an aqueous phase with excellent conversion rates and enantioselectivities (>90% ee).

Indexed as

CatalysisAmino AcidsHydrogenationKetonesMolecular StructureNanostructuresPeptidesRutheniumStereoisomerismWaterAmino AcidsKetonesPeptidesRutheniumWaterATHcatalysisenantioselectivemicellepeptideself-assemblyvesicle

Identifiers

PMID31314486
PMCPMC7235949
OpenAlexW2959075057

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.