Evidence map›Paper›PMID 31313986›Full record

ArticleeLife2019

Structural insights into flagellar stator-rotor interactions.

Yunjie Chang, Ki Hwan Moon, Xiaowei Zhao, Steven J Norris, Md A Motaleb, Jun Liu

Abstract read
In one paragraph

Article in eLife, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed.

  1. TheProceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  2. Tetrameric PilZ protein stabilizes stator ring in complex flagellar motor and is required for motility inProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
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  15. FliL ring enhances the function of periplasmic flagella.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Yunjie Chang *Department of Microbial Pathogenesis, Yale University School of Medicine, New Haven, United States.
Ki Hwan Moon *Department of Microbial Pathogenesis, Yale University School of Medicine, New Haven, United States.
Xiaowei Zhao *Microbial Sciences Institute, Yale University, West Haven, United States.
Steven J NorrisDepartment of Pathology and Laboratory Medicine, McGovern Medical School at University of Texas Health Science Center at Houston, Houston, United States.
Md A MotalebDepartment of Microbiology and Immunology, Brody School of Medicine, East Carolina University, Greenville, United States.
Jun LiuDepartment of Microbial Pathogenesis, Yale University School of Medicine, New Haven, United States.ORCID https://orcid.org/0000-0003-3108-6735

Funding

Structure-Function Relationships in the Spirochetal Flagellar MotorR01AI087946 · NIAID · YALE UNIVERSITY · PI LIU, JUN · 2010 to 2025
$6.6M
Delineation of unique flagellar proteins in spirochetesR01AI132818 · NIAID · EAST CAROLINA UNIVERSITY · PI Jun Liu, MD A MOTALEB · 2018 to 2026
$3.3M
Structural basis of signaling between bacterial chemoreceptors and flagellaR01GM107629 · NIGMS · YALE UNIVERSITY · PI LIU, JUN · 2014 to 2017
$1.5M
National Institute of Allergy and Infectious Diseases R01AI087946National Institute of Allergy and Infectious Diseases R01AI132818NIAID NIH HHS R01 AI087946NIAID NIH HHS R01 AI132818NIGMS NIH HHS R01 GM107629NIGMS NIH HHS R01GM107629
6 · The paper itself

Abstract

The bacterial flagellar motor is a molecular machine that can rotate the flagellar filament at high speed. The rotation is generated by the stator-rotor interaction, coupled with an ion flux through the torque-generating stator. Here we employed cryo-electron tomography to visualize the intact flagellar motor in the Lyme disease spirochete,

Indexed as

Bacterial ProteinsBorrelia burgdorferiElectron Microscope TomographyFlagellaMolecular Motor ProteinsMutationRotationSequence DeletionSodiumTorqueBacterial ProteinsMolecular Motor ProteinsSodiumbacterial flagellainfectious diseasemicrobiologymolecular biophysicsmotilitynanomachineprotein-protein interactionspirochetestructural biology

Identifiers

PMID31313986
PMCPMC6663468

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.