Evidence map›Paper›PMID 31313661›Full record

ArticleJMIR medical informatics2019

Improving the Efficacy of the Data Entry Process for Clinical Research With a Natural Language Processing-Driven Medical Information Extraction System: Quantitative Field Research.

Jiang Han, Ken Chen, Lei Fang, Shaodian Zhang, Fei Wang, Handong Ma, Liebin Zhao, Shijian Liu

Abstract read
In one paragraph

Article in JMIR medical informatics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jiang Han *Pediatric Translational Medicine Institute, Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China.ORCID http://orcid.org/0000-0002-4278-6617
Ken Chen *Synyi Research, Shanghai, China.ORCID http://orcid.org/0000-0003-2053-917X
Lei FangSynyi Research, Shanghai, China.ORCID http://orcid.org/0000-0002-1438-2500
Shaodian ZhangSynyi Research, Shanghai, China.ORCID http://orcid.org/0000-0002-8514-9503
Fei WangSynyi Research, Shanghai, China.ORCID http://orcid.org/0000-0002-2212-3947
Handong MaSynyi Research, Shanghai, China.ORCID http://orcid.org/0000-0002-3945-2990
Liebin ZhaoSchool of Public Health, Shanghai Jiao Tong University School of Medicine, Shanghai, China.ORCID http://orcid.org/0000-0003-2137-0177
Shijian LiuPediatric Translational Medicine Institute, Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China.ORCID http://orcid.org/0000-0002-7050-463X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe growing interest in observational trials using patient data from electronic medical records poses challenges to both efficiency and quality of clinical data collection and management. Even with the help of electronic data capture systems and electronic case report forms (eCRFs), the manual data entry process followed by chart review is still time consuming.

objectiveTo facilitate the data entry process, we developed a natural language processing-driven medical information extraction system (NLP-MIES) based on the i2b2 reference standard. We aimed to evaluate whether the NLP-MIES-based eCRF application could improve the accuracy and efficiency of the data entry process.

methodsWe conducted a randomized and controlled field experiment, and 24 eligible participants were recruited (12 for the manual group and 12 for NLP-MIES-supported group). We simulated the real-world eCRF completion process using our system and compared the performance of data entry on two research topics, pediatric congenital heart disease and pneumonia.

resultsFor the congenital heart disease condition, the NLP-MIES-supported group increased accuracy by 15% (95% CI 4%-120%, P=.03) and reduced elapsed time by 33% (95% CI 22%-42%, P<.001) compared with the manual group. For the pneumonia condition, the NLP-MIES-supported group increased accuracy by 18% (95% CI 6%-32%, P=.008) and reduced elapsed time by 31% (95% CI 19%-41%, P<.001).

conclusionsOur system could improve both the accuracy and efficiency of the data entry process.

Indexed as

case report formelectric medical recordselectronic data capturefield researchnatural language processing

Identifiers

PMID31313661
PMCPMC6672807

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.