ArticleHuman brain mapping2019
Functional network connectivity impairments and core cognitive deficits in schizophrenia.
Article in Human brain mapping, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers, 3 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
55 citing papers in PubMed, 3 syntheses or guidelines pooled it, 93 citations in OpenAlex.
- Processing Speed Impairment in Schizophrenia: An Updated Systematic Review and Meta-Analysis.JAMA psychiatry · 2026Pooled it
- Aberrant cortical-subcortical-cerebellar connectivity in resting-state fMRI as an imaging marker of schizophrenia and psychosis: a systematic review of data-driven whole-brain functional connectivity analyses.Frontiers in neuroimaging · 2025Pooled it
- A technical review of canonical correlation analysis for neuroscience applications.Human brain mapping · 2020Pooled it
- Transcranial direct current stimulation and cognitive training in the treatment of cognitive deficit in schizophrenia: a randomized controlled trial.BMC psychiatry · 2026Trial
- A Canonical Correlation Approach Towards Identifying Latent Neurofeedback Responses in Patients with Schizophrenia.Applied psychophysiology and biofeedback · 2025Trial
- Relationships between early age at onset of psychotic symptoms and treatment resistant schizophrenia.Early intervention in psychiatry · 2022Trial
- Effects of ketamine and midazolam on resting state connectivity and comparison with ENIGMA connectivity deficit patterns in schizophrenia.Human brain mapping · 2020Trial
- An interpretable cross-attentive multi-modal MRI fusion framework for schizophrenia identification.Neuroimage. Reports · 2026Article
- Dynamic Estimation of Spatially Interactive Networks (DESINE) Reveals Constrained Brain Repertoire in Schizophrenia Linked to Clinical and Cognitive Symptoms.bioRxiv : the preprint server for biology · 2026Article
- Diminished spatial dynamics and maladaptive spatial complexity link resting brain network disruption to cognition in schizophrenia.bioRxiv : the preprint server for biology · 2025Article
- Reducing functional dysconnectivity in people with schizophrenia spectrum disorders.BJPsych open · 2025Article
- st-DenseViT: A Weakly Supervised Spatiotemporal Vision Transformer for Dense Prediction of Dynamic Brain Networks.Human brain mapping · 2025Article
- Research on the correlation of nitric oxide-induced neuronal cell pyroptosis with schizophrenia and its cognitive impairment.BMC psychiatry · 2025Article
- Semantic locality-aware biclustering for brain functional network connectivity.Scientific reports · 2025Article
- Predicting Regional Cerebral Blood Flow Using Voxel-Wise Resting-State Functional MRI.Brain sciences · 2025Article
- Disentangling shared and unique brain functional changes associated with clinical severity and cognitive phenotypes in schizophrenia via deep learning.Communications biology · 2025Article
- Altered Brain-Behavior Association During Resting State is a Potential Psychosis Risk Marker.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- aNy-way ICA and its application to estimate cortico-thalamo-cerebellar functional links in schizophrenia.bioRxiv : the preprint server for biology · 2025Article
- Altered patterns of dynamic functional connectivity of brain networks in deficit and non-deficit schizophrenia.European archives of psychiatry and clinical neuroscience · 2025Article
- Functional Connectivity-Based Searchlight Multivariate Pattern Analysis for Discriminating Schizophrenia Patients and Predicting Clinical Variables.Schizophrenia bulletin · 2024Article
Corrections and comments
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Authors and funding
11 authors at 2 institutions in 1 country.
Funding
Abstract
Cognitive deficits contribute to functional disability in patients with schizophrenia and may be related to altered functional networks that serve cognition. We evaluated the integrity of major functional networks and assessed their role in supporting two cognitive functions affected in schizophrenia: processing speed (PS) and working memory (WM). Resting-state functional magnetic resonance imaging (rsfMRI) data, N = 261 patients and 327 controls, were aggregated from three independent cohorts and evaluated using Enhancing NeuroImaging Genetics through Meta Analysis rsfMRI analysis pipeline. Meta- and mega-analyses were used to evaluate patient-control differences in functional connectivity (FC) measures. Canonical correlation analysis was used to study the association between cognitive deficits and FC measures. Patients showed consistent patterns of cognitive and resting-state FC (rsFC) deficits across three cohorts. Patient-control differences in rsFC calculated using seed-based and dual-regression approaches were consistent (Cohen's d: 0.31 ± 0.09 and 0.29 ± 0.08, p < 10
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.