ArticleDevelopmental medicine and child neurology2020
Optimal clinical management of children receiving ketogenic parenteral nutrition: a clinical practice guide.
Article in Developmental medicine and child neurology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07496749 (Ketogenic Diet Treatment for Super-refractory Status Epilepticus), which is not on this map. Cited by 13 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Ketogenic Diet Treatment for Super-refractory Status Epilepticus: a Multicenter, Prospective, Randomized, Controlled Trial
Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.
- Classical and Modified Ketogenic Diets for Children and Young People With Drug-Resistant Epilepsy: A Reflection of International Dietetic Practice and Best Practice Recommendations for Dietitians.Journal of human nutrition and dietetics : the official journal of the British Dietetic Association · 2025Pooled it
- Consensus Guidelines for Diagnosis and Management of Pyruvate Dehydrogenase Complex Deficiency.Journal of inherited metabolic disease · 2026Review
- Ketogenic diet therapy for children with super-refractory status epilepticus in intensive care: International clinical practice recommendations.Epilepsia open · 2026Review
- Article
- Clinical research framework proposal for ketogenic metabolic therapy in glioblastoma.BMC medicine · 2024Review
- Unraveling unmet needs in ketogenic dietary services: An ERN EpiCARE survey.Epilepsia open · 2024Article
- Ketogenic diet treatment for super-refractory status epilepticus in the intensive care unit: feasibility, safety and effectiveness.Frontiers in neurology · 2024Article
- Classic ketogenic diet in parenteral nutrition in a GLUT1DS patient: Doing more with less in an acute surgical setting.Frontiers in nutrition · 2023Article
- Review
- Significant Published Articles in 2020 for Pharmacy Nutrition Support Practice.Hospital pharmacy · 2021Article
- Ketogenic Diet in the Treatment of Super-Refractory Status Epilepticus at a Pediatric Intensive Care Unit: A Single-Center Experience.Frontiers in neurology · 2021Article
- Application of ketogenic diets for pediatric neurocritical care.Biomedical journal · 2020Review
- Ketogenic Dietary Therapy Controversies for Its Second Century.Epilepsy currents · 2020Article
Corrections and comments
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Authors and funding
8 authors at 8 institutions in 4 countries.
Funding
Abstract
aimTo give evidence-based recommendations on the application of ketogenic diet parenteral nutrition (KD-PN) in emergency situations.
methodAn international group of experts (n=14) researched the literature and distributed a survey among 150 expert centers. International accepted guidelines (European Society for Clinical Nutrition and Metabolism/European Society for Paediatric Gastroenterology Hepatology and Nutrition and the American Society for Parenteral and Enteral Nutrition) and handbooks for parenteral nutrition were considered general standards of care.
resultsIn the literature, we identified 35 reports of patients treated by KD-PN. International guidelines and handbooks provided some conflicting information. Twenty-four expert teams from nine countries responded to the survey, reflecting the limited clinical experience.
interpretationThis paper highlights 23 consensus-based recommendations for safe and effective KD-PN (e.g. diet initiation, calculation, application, monitoring, and evaluation) based on the best evidence available and expert opinions. WHAT THIS PAPER ADDS: In acute settings, ketogenic diet therapy (KDT) can be administered parenterally. Parenteral administration of KDT should be started only at the intensive care unit. Initiate ketogenic parenteral nutrition stepwise to the highest ratio possible with the lowest level of complications. Evaluate the risk-benefit ratio of parenteral administration continuously. Restart enteral feeding as soon as appropriate.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.