Evidence map›Paper›PMID 31313220›Full record

ArticleOphthalmology and therapy2019

Dyskeratosis Congenita and Corneal Refractive Surgery.

Madeline B Heiland, Majid Moshirfar, David B Rosen, Yasmyne C Ronquillo, Phillip C Hoopes

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Ophthalmology and therapy, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Madeline B HeilandThe University of Arizona College of Medicine-Phoenix, Phoenix, AZ, USA.
Majid MoshirfarJohn A. Moran Eye Center, Department of Ophthalmology and Visual Sciences, University of Utah School of Medicine, Salt Lake City, UT, USA. cornea2020@me.com.ORCID http://orcid.org/0000-0003-1024-6250
David B RosenThe University of Arizona College of Medicine-Phoenix, Phoenix, AZ, USA.
Yasmyne C RonquilloHoopes Durrie Rivera Research Center, Hoopes Vision, Draper, UT, USA.
Phillip C HoopesHoopes Durrie Rivera Research Center, Hoopes Vision, Draper, UT, USA.
Hoopes Vision · USUniversity of Arizona · USUniversity of Utah · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dyskeratosis congenita is a syndrome of bone marrow failure secondary to unstable telomeres. It is characterized by a range of mucocutaneous diseases. Due to premature telomere shortening, these patients have limbal stem cell deficiency leading to poor regeneration and maintenance of the cornea. Many of these patients will require hematopoietic stem cell transplant in their lifetime, which poses a significant risk for acute and chronic graft-versus-host disease with and without ocular manifestations. We advise against elective corneal refractive surgery in patients with dyskeratosis congenita due to the compounded and long-term risks of delayed healing secondary to limbal stem cell deficiency and ocular complications of graft-versus-host disease post-allogeneic hematopoietic stem cell transplant.

Indexed as

Bone marrow failureCornea refractive surgeryDyskeratosis congenitaGraft-versus-host diseaseLaser in situ keratomileusis (LASIK)Limbal stem cell deficiencyOcular manifestations of graft-versus-host diseasePhotorefractive keratectomy (PRK)Small-incision lenticule extraction (SMILE)Telomeres

Identifiers

PMID31313220
PMCPMC6692790
OpenAlexW2962366980

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.