ReviewCurrent nutrition reports2019
Nutrition and Metabolic Profiles in the Natural History of Dementia: Recent Insights from Systems Biology and Life Course Epidemiology.
Review in Current nutrition reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed, 23 citations in OpenAlex.
- Age-dependent alterations of TRPA1 and urocortin 1 signaling in the Edinger-Westphal nucleus in a mouse model of Alzheimer's disease.Scientific reports · 2026Article
- Socio-environmental and health-related factors and their association with longitudinal change in brain neuroimaging markers through the plasma metabolome among UK adults: An additive Bayesian network analysis.Brain, behavior, & immunity - health · 2025Article
- Precision Nutrition and Gut-Brain Axis Modulation in the Prevention of Neurodegenerative Diseases.Nutrients · 2025Review
- Causal Association between Circulating Metabolites and Dementia: A Mendelian Randomization Study.Nutrients · 2024Article
- Identifying dementia from cognitive footprints in hospital records among Chinese older adults: a machine-learning study.The Lancet regional health. Western Pacific · 2024Article
- Diet patterns and cognitive performance in a UK Female Twin Registry (TwinsUK).Alzheimer's research & therapy · 2024Article
- Plasma metabolic profiles predict future dementia and dementia subtypes: a prospective analysis of 274,160 participants.Alzheimer's research & therapy · 2024Article
- Measures of MRI Brain Biomarkers in Middle Age According to Average Modified Mediterranean Diet Scores Throughout Young and Middle Adulthood.Nutrition and healthy aging · 2023Article
- Unlocking Modifiable Risk Factors for Alzheimer's Disease: Does the Oral Microbiome Hold Some of the Keys?Journal of Alzheimer's disease : JAD · 2023Review
- Nutrition state of science and dementia prevention: recommendations of the Nutrition for Dementia Prevention Working Group.The lancet. Healthy longevity · 2022Article
- Early signature in the blood lipidome associated with subsequent cognitive decline in the elderly: A case-control analysis nested within the Three-City cohort study.EBioMedicine · 2021Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purpose of reviewWorldwide, approximately 50 million people have dementia (mostly Alzheimer's disease). Dementia results from a multicomponent pathophysiology that follows complex dynamics over many years before symptoms become apparent. Nutrition may represent a target of choice for the primary prevention of dementia; however, there is still no firm answer on how to prevent dementia efficiently. We provide a broad overview of recent studies leveraging system biology and life-long epidemiology to address the multidimensionality and dynamical patterns underlying dementia and improve knowledge on the link between nutrition, cardiometabolic health and dementia risk. RECENT
findingsThe aging of reference population-based cohort studies, the increasing availability of cutting-edge biomarkers (e.g., brain imaging, metabolomics) and the refinement of statistical tools to model complex exposures and dynamical health outcomes have yielded substantial progress in the understanding of dementia. Systems biology coupled with life-course epidemiology will pave the way toward novel precision nutrition approaches for prevention and management of dementia.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.