ArticlePediatric cardiology2019
Procalcitonin Concentration Measured Within the First Days of Cardiac Surgery Is Predictive of Postoperative Infections in Neonates: A Case-Control Study.
Article in Pediatric cardiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 12 citations in OpenAlex.
- Clinical risk factors for postoperative infection in adult cardiac surgery with cardiopulmonary bypass: a retrospective study.Infection prevention in practice · 2025Article
- Noninfectious influencers of early-onset sepsis biomarkers.Pediatric research · 2022Review
- Classifying Infection Risk Following Pediatric Cardiac Surgery.AMIA ... Annual Symposium proceedings. AMIA Symposium · 2022Article
- Common inflammatory markers after cardiac surgery in infants and their relation to blood stream sepsis.Heliyon · 2019Article
- C-Reactive protein kinetics after cardiac surgery: A retrospective multicenter study.Annals of cardiac anaesthesiaArticle
- Combining procalcitonin, c-reactive protein, and white blood cell count in predicting infections in pediatric open cardiac surgery with cardiopulmonary bypass.Jornal de pediatriaObservational
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Increased procalcitonin concentration (PCT) is known to be reliable for the identification of infections even in the presence of the non-specific systemic inflammatory response seen after cardiopulmonary bypass (CPB), whereas increased C-reactive protein concentration (CRP) is not. The present work explored the ability of neonate PCT measured early after cardiac surgery to identify postoperative infections. This was a retrospective case-control study, where PCT was matched between patients with and without infections according to the patient's age, the CPB length, the use of deep hypothermic circulatory arrest (DHCA), and the postoperative day (POD). The accuracy in the prediction of infections was ascertained and cutoff thresholds were identified. 144 neonates were eligible, and 89 pairs of measurements from 94 patients were analyzed. PCT was a good predictor of infections within POD4, and was a better predictor when compared with CRP at POD1 and POD2. The sum of PCT (pg mL
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Registered trials
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