ArticleThe archives of bone and joint surgery2019
Operative Time Directly Correlates with Blood Loss and Need for Blood Transfusion in Total Joint Arthroplasty.
Article in The archives of bone and joint surgery, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 2 of them syntheses that pooled it.
What it found
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The trial behind it
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Who cites it
23 citing papers in PubMed, 2 syntheses or guidelines pooled it, 40 citations in OpenAlex.
- Comparing direct anterior approach versus posterior approach or lateral approach in total hip arthroplasty: a systematic review and meta-analysis.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2023Pooled it
- Cannulated screws versus dynamic hip screw versus hemiarthroplasty versus total hip arthroplasty in patients with displaced and non-displaced femoral neck fractures: a systematic review and frequentist network meta-analysis of 5703 patients.Journal of orthopaedic surgery and research · 2023Pooled it
- Safety of one-stage bilateral total knee arthroplasty -one surgeon sequential vs. two surgeons simultaneous: a randomized controlled study.International orthopaedics · 2020Trial
- Comparison of conversion unicompartmental knee arthroplasties to primary and revision total knee arthroplasties: A gradient of complexity.Journal of clinical orthopaedics and trauma · 2026Article
- Hidden blood loss after proximal femur fractures fixation: analysis of the first three postoperative days and influence of anticoagulants.Archives of orthopaedic and trauma surgery · 2026Article
- Longer operative time is associated with higher risk of adverse outcomes in pediatric idiopathic scoliosis surgery.Spine deformity · 2026Article
- Article
- Complex primary total knee arthroplasty with constrained condylar knee in post-traumatic arthritis: a retrospective comparison between 3D-printed patient-specific instrumentation and conventional instrumentation.Journal of orthopaedic surgery and research · 2025Article
- Short-Term Outcomes of Noncemented Total Knee Arthroplasty in Patients With Morbid Obesity.Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews · 2025Article
- Enhancing bleeding control in total knee arthroplasty for osteoarthritis and rheumatic diseases: strategies and insights.Reumatologia · 2025Review
- Direct Anterior vs. Posterior Approach in Simultaneous Bilateral Total Hip Arthroplasty: A Meta-Analysis.Cureus · 2024Review
- Evidence-based Approach for Prevention of Surgical Site Infection.Hip & pelvis · 2024Review
- Are Routine Postoperative Hemoglobin Tests Justified in All Patients Who Undergo Total Hip Arthroplasty Due to a Displaced Femoral Neck Fracture?Journal of clinical medicine · 2024Article
- Are robotic-assisted and computer-navigated total hip arthroplasty associated with superior outcomes in patients who have hip dysplasia?Journal of orthopaedics · 2024Review
- Total Joint Arthroplasty and Sleep: The State of the Evidence.Arthroplasty today · 2024Article
- Influence of Surgery Preparation Time on Patient Outcomes.Journal of nursing management · 2024Article
- The efficacy and safety of tranexamic acid in transforaminal lumbar interbody fusion: a systematic review and meta-analysis.EFORT open reviews · 2023Article
- Managing surgery in hemophilia with recombinant factor VIII Fc and factor IX Fc: Data on safety and effectiveness from phase 3 pivotal studies.Research and practice in thrombosis and haemostasis · 2022Article
- Development and validation of a nomogram to predict complications in patients undergoing simultaneous bilateral total knee arthroplasty: A retrospective study from two centers.Frontiers in surgery · 2022Article
- The role of preoperative dutasteride in reducing bleeding during transurethral resection of the prostate: A systematic review and meta-analysis of randomized controlled trials.Asian journal of urology · 2022Article
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAllogeneic blood transfusion in patients undergoing total joint arthroplasty (TJA) has been shown to negatively affect patient outcomes. This study aimed to examine if there is a correlation between operative time and the need for allogeneic blood transfusions during TJA.
methodsWe performed a retrospective review of 866 patients who underwent primary TJA during a one-year period at our institution. Logistic regression was performed to identify the association between operative time and need for allogeneic blood transfusion, controlling for other patient and surgical factors. Multiple linear regression analysis was also performed to see how the same factors affected CBL.
resultsOf the 866 cases, 13%(115) were simultaneous bilateral. 52%(449) of patients received preoperative autologous blood donation. The average operative time for unilateral and bilateral patients was 74.1±(33.9) and 132.6±(36.0) minutes, respectively. Average CBL for unilateral patients was 2120mL±(1208) and 4051mL±(1311) for bilateral cases. The average number of allogeneic transfusions was also higher within the bilateral group (0.49 vs 1.15 units). Multivariate analysis indicated that duration of surgery (odds ratio [OR]:1.35 per 15 minutes) and bilateral TJA (OR: 2.97) increase the risk of allogeneic blood transfusion, while patients having total knee arthroplasty are less likely to receive allogeneic blood transfusion (OR: 0.50). CBL also increased significantly with surgical duration (211.5 mL per 15 minutes).
conclusionA subgroup analysis confirmed that there was a correlation between operative time and need for allogeneic transfusion following unilateral TJA. Expeditious surgery can minimize blood loss and subsequent need for blood transfusion and its associated adverse consequences. LEVEL OF EVIDENCE: III.
Indexed as
Identifiers
31312679PMC6578479W2912132062What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.