Evidence map›Paper›PMID 31312671›Full record

ArticleNeurophotonics2019

Monitoring retinal responses to acute intraocular pressure elevation in rats with visible light optical coherence tomography.

Shaohua Pi, Tristan T Hormel, Xiang Wei, William Cepurna, Acner Camino, Yukun Guo, David Huang, John Morrison, Yali Jia

Open access · goldAbstract read
In one paragraph

Article in Neurophotonics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.6field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 26 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Widefield OCT angiography.Progress in retinal and eye research · 2025
    Review
  5. Review
  6. Controlled Elevation of Intraocular Pressure (CEI) Glaucoma Model in Rats.Methods in molecular biology (Clifton, N.J.) · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Retinal capillary oximetry with visible light optical coherence tomography.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Shaohua PiOregon Health and Science University, Casey Eye Institute, Portland, Oregon, United States.ORCID https://orcid.org/0000-0002-7549-8929
Tristan T HormelOregon Health and Science University, Casey Eye Institute, Portland, Oregon, United States.
Xiang WeiOregon Health and Science University, Casey Eye Institute, Portland, Oregon, United States.
William CepurnaOregon Health and Science University, Casey Eye Institute, Portland, Oregon, United States.ORCID https://orcid.org/0000-0002-0509-9041
Acner CaminoOregon Health and Science University, Casey Eye Institute, Portland, Oregon, United States.
Yukun GuoOregon Health and Science University, Casey Eye Institute, Portland, Oregon, United States.
David HuangOregon Health and Science University, Casey Eye Institute, Portland, Oregon, United States.ORCID https://orcid.org/0000-0003-2592-8393
John MorrisonOregon Health and Science University, Casey Eye Institute, Portland, Oregon, United States.
Yali JiaOregon Health and Science University, Casey Eye Institute, Portland, Oregon, United States.ORCID https://orcid.org/0000-0002-2784-1905
Oregon Health & Science University · US

Funding

Proteomics CoreP30EY010572 · NEI · OREGON HEALTH & SCIENCE UNIVERSITY · PI Kate E Keller · 1995 to 2026
$19.4M
STUDIES IN GLAUCOMATOUS OPTIC NERVE DAMAGER01EY010145 · NEI · OREGON HEALTH & SCIENCE UNIVERSITY · PI MORRISON, JOHN C · 1993 to 2023
$8.9M
Functional and Structural Optical Coherence Tomography for GlaucomaR01EY023285 · NEI · OREGON HEALTH & SCIENCE UNIVERSITY · PI David Huang · 2013 to 2026
$8.8M
OCT Angiography for Neovascular Age-related Macular DegenerationR01EY024544 · NEI · OREGON HEALTH & SCIENCE UNIVERSITY · PI Steven T Bailey, Yali Jia · 2014 to 2026
$6.2M
In Vivo Molecular Imaging of the RetinaR01EY023397 · NEI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI PENN, JOHN S., UDDIN, MD IMAM · 2013 to 2022
$3.6M
Wide-field and projection-resolved optical coherence tomography angiography in diabetic retinopathyR01EY027833 · NEI · OREGON HEALTH & SCIENCE UNIVERSITY · PI HWANG, THOMAS, JIA, YALI · 2017 to 2020
$1.8M
Functional Optical Coherence Tomography-derived Biomarkers for Diabetic RetinopathyDP3DK104397 · NIDDK · OREGON HEALTH & SCIENCE UNIVERSITY · PI JIA, YALI, WILSON, DAVID J · 2014 to 2014
$1.0M
NEI NIH HHS P30 EY010572NEI NIH HHS R01 EY010145NEI NIH HHS R01 EY023285NEI NIH HHS R01 EY023397NEI NIH HHS R01 EY024544NEI NIH HHS R01 EY027833NIDDK NIH HHS DP3 DK104397
6 · The paper itself

Abstract

Elevated intraocular pressure (IOP) is an important risk factor for glaucoma. However, the role of IOP in glaucoma progression, as well as retinal physiology in general, remains incompletely understood. We demonstrate the use of visible light optical coherence tomography to measure retinal responses to acute IOP elevation in Brown Norway rats. We monitored retinal responses in reflectivity, angiography, blood flow, oxygen saturation (

Indexed as

functional monitoring and imagingglaucomaoptical coherence tomographyoxygen metabolismtotal retinal blood flow

Identifiers

PMID31312671
PMCPMC6624745
OpenAlexW2957287400

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.