Evidence map›Paper›PMID 31312613›Full record

ArticleFrontiers in oncology2019

Electro-Acupuncture Promotes Accumulation of Paclitaxel by Altering Tumor Microvasculature and Microenvironment in Breast Cancer of Mice.

Ming Yang, Yuxiang Wan, Xin Jiang, Xuewei Qi, Lina Wang, Zeyu Liu, Xiaojing Song, Lin Pan, Weiliang Sun, Wei Zhao and 2 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in oncology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
4.1field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
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  4. Advances in Medical Devices for Augmented Acupuncture Therapy.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Review
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  6. [Preliminary Study on Microvasculature Normalization Induced by Peritumoral Electroacupuncture in Mice With Breast Cancer Xenografts].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2023
    Article
  7. Article
  8. Review
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  10. Review
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Ming YangSchool of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing, China.
Yuxiang WanBeijing University of Chinese Medicine Third Affiliated Hospital, Beijing, China.
Xin JiangSchool of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing, China.
Xuewei QiBeijing University of Chinese Medicine Third Affiliated Hospital, Beijing, China.
Lina WangBeijing University of Chinese Medicine Third Affiliated Hospital, Beijing, China.
Zeyu LiuBeijing University of Chinese Medicine Third Affiliated Hospital, Beijing, China.
Xiaojing SongDepartment of Biomedical Engineering, Institute of Acupuncture and Moxibustion, China Academy of Chinese Medical Sciences, Beijing, China.
Lin PanInstitute of Clinical Medical Science, China-Japan Friendship Hospital, Beijing, China.
Weiliang SunInstitute of Clinical Medical Science, China-Japan Friendship Hospital, Beijing, China.
Wei ZhaoGuanganmen Hospital, Chinese Academy of Traditional Chinese Medicine, Beijing, China.
Jinchang HuangBeijing University of Chinese Medicine Third Affiliated Hospital, Beijing, China.
Zenglin LianInstitute of Biological Chinese Medicine, Beijing Yichuang Institute of Biotechnology Industry, Beijing, China.
Beijing University of Chinese Medicine · CNChina-Japan Friendship Hospital · CNChinese Academy of Medical Sciences & Peking Union Medical College · CNGuang’anmen Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Targeted drug delivery could increase the efficacy of chemotherapy, however, a plethora of obstacles exist in the current targeted delivery designs. In this study, we introduce a novel avenue of targeted drug delivery using electro-acupuncture and evaluate its effect on the distribution of paclitaxel in a breast cancer mouse model. Our results show that electro-acupuncture intervention significantly increased the intratumoral concentration of paclitaxel. The mice in acupuncture group showed shorter

Indexed as

acupuncturebreast cancermicroenvironmentpaclitaxeltargeted drug delivery

Identifiers

PMID31312613
PMCPMC6614178
OpenAlexW2951894867

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.