Evidence map›Paper›PMID 31312417›Full record

ReviewComputational and structural biotechnology journal2019

Base-pair Opening Dynamics of Nucleic Acids in Relation to Their Biological Function.

Seo-Ree Choi, Na-Hyun Kim, Ho-Seong Jin, Yeo-Jin Seo, Juhyun Lee, Joon-Hwa Lee

Abstract readReview
In one paragraph

Review in Computational and structural biotechnology journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Nucleic acid base pair open states by hydrogen exchange.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  3. Hyperpolarized NMR Reveals Low-Populated Folding Intermediates in DNA.Journal of the American Chemical Society · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. ACS physical chemistry Au · 2022
    Article
  10. Article
  11. Article
  12. Dynamics Studies of DNA with Non-canonical Structure Using NMR Spectroscopy.International journal of molecular sciences · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Seo-Ree ChoiDepartment of Chemistry and RINS, Gyeongsang National University, Gyeongnam 52828, South Korea.
Na-Hyun KimDepartment of Chemistry and RINS, Gyeongsang National University, Gyeongnam 52828, South Korea.
Ho-Seong JinDepartment of Chemistry and RINS, Gyeongsang National University, Gyeongnam 52828, South Korea.
Yeo-Jin SeoDepartment of Chemistry and RINS, Gyeongsang National University, Gyeongnam 52828, South Korea.
Juhyun LeeDepartment of Chemistry, KAIST, Daejeon 34141, South Korea.
Joon-Hwa LeeDepartment of Chemistry and RINS, Gyeongsang National University, Gyeongnam 52828, South Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Base-pair opening is a conformational transition that is required for proper biological function of nucleic acids. Hydrogen exchange, observed by NMR spectroscopic experiments, is a widely used method to study the thermodynamics and kinetics of base-pair opening in nucleic acids. The hydrogen exchange data of imino protons are analyzed based on a two-state (open/closed) model for the base-pair, where hydrogen exchange only occurs from the open state. In this review, we discuss examples of how hydrogen exchange data provide insight into several interesting biological processes involving functional interactions of nucleic acids:

Indexed as

Base-pair openingDNAHydrogen exchangeNMRNucleic acidsRNA

Identifiers

PMID31312417
PMCPMC6607312

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.