Evidence map›Paper›PMID 31312373›Full record

ArticleAmerican journal of translational research2019

Influence of the plasminogen activator system on necrosis in acute myocardial infarction: analysis of urokinase- and urokinase receptor-knockout mouse models.

Joerg Herold, Felix M Heidrich, Silvio Quick, Tobias Loehn, Karim Ibrahim, Adrian Mahlmann, Akram Youssef

Open access · greenAbstract read
PubMed Full text at PMC
In one paragraph

Article in American journal of translational research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.1field-weighted citation impact, top 56% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Joerg HeroldDepartment of Vascular Medicine, Klinikum Darmstadt GmbH Darmstadt, Germany.
Felix M HeidrichDepartment for Internal Medicine and Cardiology, Herzzentrum Dresden, University Clinic, Technische Universität Dresden Germany.
Silvio QuickDepartment for Internal Medicine and Cardiology, Herzzentrum Dresden, University Clinic, Technische Universität Dresden Germany.
Tobias LoehnDepartment for Internal Medicine and Cardiology, Herzzentrum Dresden, University Clinic, Technische Universität Dresden Germany.
Karim IbrahimDepartment for Internal Medicine and Cardiology, Herzzentrum Dresden, University Clinic, Technische Universität Dresden Germany.
Adrian MahlmannUniversity Centre for Vascular Medicine and Department of Medicine-Section Angiology, University Hospital Carl Gustav Carus at The Technische Universität Dresden Germany.
Akram YoussefDepartment for Internal Medicine and Cardiology, Herzzentrum Dresden, University Clinic, Technische Universität Dresden Germany.
TU Dresden · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Serine proteases and G-protein-coupled receptors have been studied extensively as effectors of cell death. However, their roles in myocardial infarction have not been determined. In this study, we investigated the influence of the plasminogen activator system involving urokinase and urokinase receptor on necrosis after acute myocardial infarction. Myocardial infarction and reperfusion were induced in mouse hearts using the

Indexed as

Apoptosisinfarctionmatrix metalloproteinasesreperfusiontransgenic animal models

Identifiers

PMID31312373
PMCPMC6614646
OpenAlexW2997138511

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.