Evidence map›Paper›PMID 31312367›Full record

ArticleAmerican journal of translational research2019

Suppression of murine B-cell lymphoma growth by trichosanthin through anti-angiogenesis.

Xingbin Dai, Pengjun Jiang, Yanhua Ji, Xuejun Zhu, Xuemei Sun

Open access · greenAbstract read
PubMed Full text at PMC
In one paragraph

Article in American journal of translational research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Study of Water- and Organic-Soluble Extracts fromJournal of diabetes research · 2022
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Xingbin DaiDepartment of Hematology, Affiliated Hospital of Nanjing University of Chinese Medicine Nanjing 210029, China.
Pengjun JiangFirst Clinical Medical College, Nanjing University of Chinese Medicine Nanjing 210029, China.
Yanhua JiSchool of Life Science & Technology, China Pharmaceutical University Nanjing 210009, China.
Xuejun ZhuFirst Clinical Medical College, Nanjing University of Chinese Medicine Nanjing 210029, China.
Xuemei SunFirst Clinical Medical College, Nanjing University of Chinese Medicine Nanjing 210029, China.
China Pharmaceutical University · CNNanjing University of Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Studies have suggested trichosanthin (TCS) exerts antitumor activity mainly through direct cytotoxicity toward cancer cells and immune regulation. In this study, we conducted the proliferation and apoptosis assay on A20 cells and endothelial cells (ECs) with different concentrations of TCS and investigated the levels of gene expression linked to angiogenesis. Herein, a new mechanism that TCS inhibits murine B-cell lymphoma growth by anti-angiogenesis was reported. First, TCS inhibit tumor growth and prolonged survival significantly

Indexed as

A20 cellsangiogenesisendothelial cellslymphomaTrichosanthinvascular endothelial growth factor

Identifiers

PMID31312367
PMCPMC6614629
OpenAlexW2980880862

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.