ArticleAmerican journal of translational research2019
Loquat leaf polysaccharides improve glomerular injury in rats with anti-Thy 1 nephritis via peroxisome proliferator-activated receptor alpha pathway.
Article in American journal of translational research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed, 8 citations in OpenAlex.
- Four sesquiterpene glycosides from loquat (PeerJ · 2020Article
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Chronic glomerulonephritis frequently develops into renal failure that cannot be completely cured. Based on the success of anti-inflammatory Chinese herbs in treating chronic nephritis, our goal was to investigate the therapeutic effects and mechanism of action of loquat leaf polysaccharides (LLPS) on chronic anti-Thy-1 nephritis. A rat model of glomerulonephritis was used to study the effects of 8 weeks of enalapril or LLPS treatment. Twenty-four-hour rat urinary protein excretions were measured every week for 8 weeks. Then, all animals were sacrificed, renal-related biochemical parameters were analyzed, and histology and electron microscopy examinations of renal tissue samples were conducted. Renal cortex tissue was used to detect markers of renal fibrosis. RNA sequencing (RNA-seq) and
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31312364PMC6614611W2980698450What OpenQuestion holds
Registered trials
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