ArticleAmerican journal of translational research2019
Insulin treatment enhances pseudomonas aeruginosa biofilm formation by increasing intracellular cyclic di-GMP levels, leading to chronic wound infection and delayed wound healing.
Article in American journal of translational research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 15 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.
- Wound Healing Impairment in Type 2 Diabetes Model of Leptin-Deficient Mice-A Mechanistic Systematic Review.International journal of molecular sciences · 2022Pooled it
- Insulin Affects Biological Behaviours ofPharmaceuticals (Basel, Switzerland) · 2026Article
- Proactive Strategies to Prevent Biofilm-Associated Infections: From Mechanistic Insights to Clinical Translation.Microorganisms · 2025Review
- Review
- Harnessing Cyclic di-GMP Signaling: A Strategic Approach to Combat Bacterial Biofilm-Associated Chronic Infections.Current microbiology · 2025Review
- Insight on Infections in Diabetic Setting.Biomedicines · 2023Review
- Biofilm-Associated Infections in Chronic Wounds and Their Management.Advances in experimental medicine and biology · 2023Article
- DNase inhibits early biofilm formation inFrontiers in cellular and infection microbiology · 2022Article
- Production and Characterization of Exopolysaccharide From Newly Isolated Marine ProbioticFrontiers in microbiology · 2022Article
- Genome characterization of a uropathogenicFrontiers in cellular and infection microbiology · 2022Article
- The Insights of Microbes' Roles in Wound Healing: A Comprehensive Review.Pharmaceutics · 2021Review
- Biofilm Formation byFrontiers in cellular and infection microbiology · 2021Article
- The effect of Cyclic-di-GMP on biofilm formation byAnnals of translational medicine · 2020Article
- miR-27-3p inhibition restore fibroblasts viability in diabetic wound by targeting NOVA1.Aging · 2020Article
- Bafilomycin A1 Accelerates Chronic Refractory Wound Healing in db/db Mice.BioMed research international · 2020Article
Corrections and comments
- Erratum issued
Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Diabetes-related infections have become challenging and important public health problems in China and around the world.
Indexed as
Identifiers
31312343PMC6614630W2986531338What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.