Evidence map›Paper›PMID 31312334›Full record

ArticleThe Pan African medical journal2019

A multi-centre evaluation of malignant odontogenic tumours in Nigeria.

Olujide Oladele Soyele, Olajumoke Ajibola Effiom, Ahmed Oluwatoyin Lawal, Mark Chukwuemeka Nwoga, Kehinde Emmanuel Adebiyi, Adetayo Aborisade, Abiodun Saheed Olatunji, Adetokunbo Babajide Olawuyi, Adeola Mofoluwake Ladeji, Robinson Obos Okiti and 1 more

Open access · goldAbstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in The Pan African medical journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 2 countries.

Olujide Oladele SoyeleDepartment of Oral Maxillofacial Surgery and Oral Pathology, Obafemi Awolowo University, Ile-Ife, Nigeria.
Olajumoke Ajibola EffiomDepartment of Oral and Maxillofacial Pathology and Biology, College of Medicine, University of Lagos, Lagos, Nigeria.
Ahmed Oluwatoyin LawalDepartment of Oral Pathology, College of Medicine, University of Ibadan, Ibadan, Nigeria.
Mark Chukwuemeka NwogaOral Pathology Unit, Department of Oral and Maxillofacial Surgery, Faculty of Dentistry University of Nigeria, Enugu, Nigeria.
Kehinde Emmanuel AdebiyiDepartment of Oral Pathology and Oral Medicine, Faculty of Dentistry, Lagos State University College of Medicine, Ikeja, Lagos, Nigeria.
Adetayo AborisadeDepartment of Oral and Maxillofacial Surgery and Oral Pathology, Obafemi Awolowo University Teaching Hospital Complex, Ile-Ife, Nigeria.
Abiodun Saheed OlatunjiDepartment of Oral and Maxillofacial Surgery and Oral Pathology, Obafemi Awolowo University Teaching Hospital Complex, Ile-Ife, Nigeria.
Adetokunbo Babajide OlawuyiDepartment of Oral and Maxillofacial Pathology and Biology, Lagos University Teaching Hospital, Lagos, Nigeria.
Adeola Mofoluwake LadejiDepartment of Oral Pathology and Oral Medicine, Faculty of Dentistry, Lagos State University College of Medicine, Ikeja, Lagos, Nigeria.
Robinson Obos OkitiDepartment of Oral Pathology, University College Hospital, Ibadan, Nigeria.
Henry Ademola AdeolaDepartment of Oral and Maxillofacial Pathology, Faculty of Dentistry, University of the Western Cape and Tygerberg Hospital, Cape Town, South Africa.
Lagos State University · NGUniversity College Hospital, Ibadan · NGUniversity of Cape Town · ZAUniversity of Ibadan · NGUniversity of Lagos · NG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionodontogenic tumors originate from neoplastic transformation of the remnants of tooth forming apparatus. There are varying degrees of inductive interactions between odontogenic ectomesenchyme and epithelium during odontogenesis, leading to lesions that vary from benign to malignant. Malignant odontogenic tumours (MOTs) are very rare and are classified according to embryonic tissue of origin. Recently, there has been a few changes to the classification of MOTs according to the World Health Organization's (WHO) classification in 2017. This study aims to evaluate and reclassify MOTs, using a multi-centre approach in some major tertiary dental hospitals in Nigeria.

methodsthis study reviewed the clinicopathological data on 63 cases of MOT diagnosed over 25 years in five major tertiary dental hospitals in Nigeria. All MOT cases were reclassified according to the recent revision to the 2017 WHO classification of odontogenic tumours.

resultsfrom a total of 10,446 biopsies of oral and jaw lesions seen at the 5 study centres over the 25-year study period, 2199 (21.05%) cases were found to be odontogenic tumours (OTs), of which 63 were MOT. MOTs constituted 0.60% of the total biopsy cases and 2.86% of OTs. Odontogenic carcinomas presented with a mean age higher than odontogenic sarcomas. According to our 2017 WHO reclassification of MOTs, odontogenic carcinomas, ameloblastic carcinomas and primary intraosseous carcinomas were found to be the top three lesions, respectively. Carcinosarcomas were found to be extremely rare.

conclusionusing a multi-centre approach is a robust way to reduce diagnostic challenges associated with rare maxillofacial lesions such as MOTs.

Indexed as

AdolescentAdultAgedAge FactorsAmeloblastomaBiopsyCarcinosarcomaChildChild, PreschoolFemaleHumansJaw NeoplasmsMaleMiddle AgedNigeriaOdontogenic Tumorshead and neckmalignantmulti-centreNigeriaOdontogenic tumour

Identifiers

PMID31312334
PMCPMC6615768
OpenAlexW2978904763

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.