Evidence map›Paper›PMID 31312327›Full record

ArticleThe Pan African medical journal2019

Predictors of loss to follow-up among children attending HIV clinic in a hospital in rural Kenya.

Winnie Mueni Saumu, Elizabeth Maleche-Obimbo, Grace Irimu, Rashmi Kumar, Christine Gichuhi, Bundi Karau

Open access · goldAbstract read
In one paragraph

Article in The Pan African medical journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 2 pooled it
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 2 syntheses or guidelines pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Loss to Hospital Follow-Up in Pediatric Cerebral Malaria Survivors: A Case-Control Study.The American journal of tropical medicine and hygiene · 2023
    Article
  5. Article
  6. Article
  7. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Winnie Mueni SaumuDepartment of Paediatrics and Child Health, Chuka County Referral Hospital, Tharaka Nithi KE, Kenya.
Elizabeth Maleche-ObimboDepartment of Paediatrics and Child Health, University of Nairobi, Nairobi, Kenya.
Grace IrimuDepartment of Paediatrics and Child Health, University of Nairobi, Nairobi, Kenya.
Rashmi KumarDepartment of Paediatrics and Child Health, University of Nairobi, Nairobi, Kenya.
Christine GichuhiDepartment of Clinical Medicine and Therapeutics, University of Nairobi, Nairobi, Kenya.
Bundi KarauDepartment of Internal Medicine, Kenya Methodist University, Nairobi, Kenya.
University of Nairobi · KEChuka University · KEKenya Methodist University · KE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionAfrican studies have reported high rates of loss to follow up (LTFU) among children in HIV care and treatment centres. Factors associated with LTFU may vary across populations. Few studies have been conducted among HIV infected children in care in rural areas of Kenya.

methodsthis involved children aged less than 15 years on follow up at Kangundo Level 4 Hospital HIV clinic from January 2010 to December 2015. We obtained sociodemographic and clinical information from patient files and electronic databases. Univariate and multivariate regression analyses were conducted to identify factors predictive of LTFU.

resultsa total of 261 HIV-infected children were followed up. The mean age was 10.0 years (IQR, 7-13) and median CD4 count of 582cells/ul (IQR 314-984). By December 2015, 171 children (65.5%) remained in active care, 32 (12.3%) transferred out, 13 (5%) died, while 45 (17.2%) were classified as LTFU. Out of the 45 children presumed as LTFU, we traced 44 out of the 45 children (98%) and found that their actual current status was as follows: 33 of the 44 children (75.0%) had dropped out of care (true LTFU). Factors strongly predictive of LTFU included low caregiver level of education (HR 2.3, 1.9-3.9, P = 0.001), WHO stage I and II at enrolment (HR 1.6, 1.4-2.1, P = 0.05).

conclusionLTFU of HIV infected children was common with an incidence of 32.9 per 1000 child years and occurred early in treatment and risk factors included poverty, low caregiver education, male child and early HIV disease stage.

Indexed as

Lost to Follow-UpAdolescentAmbulatory Care FacilitiesCaregiversCD4 Lymphocyte CountChildChild, PreschoolCross-Sectional StudiesEducational StatusFemaleFollow-Up StudiesHIV InfectionsHumansInfantKenyaMalechildrenHIV infectedloss to follow up

Identifiers

PMID31312327
PMCPMC6620067
OpenAlexW2943222121

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.