Evidence map›Paper›PMID 31312286›Full record

ArticleBiomicrofluidics2019

An acoustofluidic platform for non-contact trapping of cell-laden hydrogel droplets compatible with optical microscopy.

Anna Fornell, Carl Johannesson, Sean S Searle, Axel Happstadius, Johan Nilsson, Maria Tenje

Open access · greenAbstract read
In one paragraph

Article in Biomicrofluidics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 20 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Anna FornellDepartment of Engineering Sciences, Science for Life Laboratory, Uppsala University, Box 534, 751 21 Uppsala, Sweden.ORCID 0000-0001-7980-376X
Carl JohannessonDepartment of Biomedical Engineering, Lund University, Box 118, 221 00 Lund, Sweden.
Sean S Searle
Axel HappstadiusDepartment of Biomedical Engineering, Lund University, Box 118, 221 00 Lund, Sweden.
Johan NilssonDepartment of Biomedical Engineering, Lund University, Box 118, 221 00 Lund, Sweden.ORCID 0000-0003-1282-9580
Maria TenjeDepartment of Engineering Sciences, Science for Life Laboratory, Uppsala University, Box 534, 751 21 Uppsala, Sweden.ORCID 0000-0002-1264-1337
Lund University · SEUppsala University · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Production of cell-laden hydrogel droplets as miniaturized niches for 3D cell culture provides a new route for cell-based assays. Such production can be enabled by droplet microfluidics and here we present a droplet trapping system based on bulk acoustic waves for handling hydrogel droplets in a continuous flow format. The droplet trapping system consists of a glass capillary equipped with a small piezoelectric transducer. By applying ultrasound (4 MHz), a localized acoustic standing wave field is generated in the capillary, trapping the droplets in a well-defined cluster above the transducer area. The results show that the droplet cluster can be retained at flow rates of up to 76

Identifiers

PMID31312286
PMCPMC6624123
OpenAlexW2960407881

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.