ArticleFrontiers in psychiatry2019
The Altered Somatic Brain Network in State Anxiety.
Article in Frontiers in psychiatry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
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Who cites it
28 citing papers in PubMed.
- Uncovering the correlation between neurotransmitter-specific functional connectivity and multidimensional anxiety in a non-clinical cohort.European archives of psychiatry and clinical neuroscience · 2026Article
- Structural brain differences associated with panic disorder: an ENIGMA-Anxiety Working Group mega-analysis of 4924 individuals worldwide.Molecular psychiatry · 2026Article
- Identifying neuroimaging biomarkers for anxiety in emerging adults using machine learning and functional near-infrared spectroscopy during resting-state.Frontiers in psychiatry · 2026Article
- Machine learning and individual variability in electrical field characteristics predict tDCS treatment response for anxiety in older adults in the ACT trial.Frontiers in human neuroscience · 2026Article
- Resilience or vulnerability? thalamic subdivision connectivity in trauma-exposed individuals: a 7 t resting-state fMRI study.Translational psychiatry · 2025Article
- Characteristic volume, texture, and functional connectivity alterations in hypothalamic subunits of adult primary hypothyroidism: a multiparametric MRI analysis.Journal of endocrinological investigation · 2025Article
- Efficacy and Safety of Electroacupuncture Through Nerve Stimulation in Patients With Anxiety Disorders: Protocol for a Randomized, Assessor-Blind, Three-Arm, Parallel-Group Clinical Trial.JMIR research protocols · 2025Article
- The Functional Anatomy of Nociception: Effective Connectivity in Chronic Pain and Placebo Response.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Functional connectivity characteristics of epilepsy with anxiety: A resting-state functional near-infrared spectroscopy study.Medicine · 2025Observational
- Intrinsic functional brain connectivity in adolescent anxiety: Associations with behavioral phenotypes and cross-syndrome network features.Journal of affective disorders · 2025Article
- Neural foundation of the diathesis-stress model: longitudinal gray matter volume changes in response to stressful life events in major depressive disorder and healthy controls.Molecular psychiatry · 2024Article
- Threat- and reward-related brain circuitry, perceived stress, and anxiety in adolescents during the COVID-19 pandemic: a longitudinal investigation.Social cognitive and affective neuroscience · 2024Article
- Brainwide Mendelian Randomization Study of Anxiety Disorders and Symptoms.Biological psychiatry · 2024Article
- Brain volumes, behavioral inhibition, and anxiety disorders in children: results from the adolescent brain cognitive development study.BMC psychiatry · 2024Article
- Article
- Sex differences in the effects of trait anxiety and age on resting-state functional connectivities of the amygdala.Journal of affective disorders reports · 2023Article
- Neural representations of anxiety in adolescents with anorexia nervosa: a multivariate approach.Translational psychiatry · 2023Article
- Life After Mild Traumatic Brain Injury: Widespread Structural Brain Changes Associated With Psychological Distress Revealed With Multimodal Magnetic Resonance Imaging.Biological psychiatry global open science · 2023Article
- Dynamic effective connectivity among large-scale brain networks mediates risk of anxiety.Human brain mapping · 2023Article
- Anxious Brains: A Combined Data Fusion Machine Learning Approach to Predict Trait Anxiety from Morphometric Features.Sensors (Basel, Switzerland) · 2023Article
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Authors and funding
7 authors.
Funding
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Abstract
Highly anxious individuals often show excessive emotional arousal, somatic arousal, and characteristics of mental illness. Previous researches have extensively investigated the emotional and cognitive biases of individuals with high anxiety, but overlooked the spontaneous brain activity and functional connections associated with somatic arousal. In this study, we investigated the relationship between state anxiety and the spontaneous brain activity of the somatosensory cortex in a non-clinical healthy population with state anxiety. Furthermore, we also explored the functional connections of the somatosensory cortex. We found that state anxiety was positively correlated with the amplitude of low-frequency fluctuations (ALFFs) of somatic related brain regions, including the right postcentral gyrus (somatosensory cortex) and the right precentral gyrus (somatic motor cortex). Furthermore, we found that state anxiety was positively correlated with the connections between the postcentral gyrus and the left cerebellum gyrus, whereas state anxiety was negatively correlated with the connectivity between the postcentral gyrus and brain regions including the left inferior frontal cortex and left medial superior frontal cortex. These results revealed the association between the anxious individuals' body-loop and state anxiety in a healthy population, which revealed the importance of somatic brain regions in anxiety symptoms and provided a new perspective on anxiety for further study.
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