ArticleFrontiers in molecular neuroscience2019
Post-retrieval Extinction Prevents Reconsolidation of Methamphetamine Memory Traces and Subsequent Reinstatement of Methamphetamine Seeking.
Article in Frontiers in molecular neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed.
- The synergy of methylphenidate- and reconsolidation-based extinction normalizes ventromedial prefrontal function in drug addiction.Proceedings of the National Academy of Sciences of the United States of America · 2025Trial
- A novel imagery-based retrieval-extinction training for intervention in nicotine addiction.BMC medicine · 2025Trial
- Effect of conditioned stimuli-triggered memory retrieval-extinction in patients with methamphetamine use disorder.Translational psychiatry · 2025Trial
- Exploring Post-Retrieval Strategies to Reduce Drug Craving in Methamphetamine Use Disorders.Addiction biology · 2025Trial
- Renewal and reacquisition of substance-associated relapse.Frontiers in psychology · 2026Review
- Memory Reconsolidation Updating in Substance Addiction: Applications, Mechanisms, and Future Prospects for Clinical Therapeutics.Neuroscience bulletin · 2025Review
- High frequency deep brain stimulation of the dorsal raphe nucleus prevents methamphetamine priming-induced reinstatement of drug seeking in rats.Translational psychiatry · 2024Article
- Article
- Task-switching mechanisms under methamphetamine cravings: sex differences in cued and voluntary task-switching.Frontiers in neuroscience · 2024Article
- Disrupting astrocyte-neuron lactate transport prevents cocaine seeking after prolonged withdrawal.Science advances · 2023Article
- Modulation of methamphetamine memory reconsolidation by neural projection from basolateral amygdala to nucleus accumbens.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2023Article
- Effects of retrieval-extinction training on internet gaming disorder.Journal of behavioral addictions · 2022Article
- Article
- Simvastatin Blocks Reinstatement of Cocaine-induced Conditioned Place Preference in Male Mice with Brain Lipidome Remodeling.Neuroscience bulletin · 2021Article
- High-Frequency Deep Brain Stimulation of the Substantia Nigra Pars Reticulata Facilitates Extinction and Prevents Reinstatement of Methamphetamine-Induced Conditioned Place Preference.Frontiers in pharmacology · 2021Article
- Molecular and circuit mechanisms regulating cocaine memory.Cellular and molecular life sciences : CMLS · 2020Review
- Postretrieval Microinjection of Baclofen Into the Agranular Insular Cortex Inhibits Morphine-Induced CPP by Disrupting Reconsolidation.Frontiers in pharmacology · 2020Article
- Destabilizing Different Strengths of Fear Memories Requires Different Degrees of Prediction Error During Retrieval.Frontiers in behavioral neuroscience · 2020Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Methamphetamine abuse has become a serious public health problem. However, effective treatment for methamphetamine addiction remains elusive, especially considering its high rate of relapse after treatment. A conditioned stimulus (CS) memory retrieval-extinction procedure has been demonstrated to decrease reinstatement of cocaine, heroin, and alcohol seeking in rats, and to reduce cue-induced cravings in heroin and nicotine addicts. The goal of the present study is to explore the effect of the CS memory retrieval-extinction procedure on methamphetamine seeking in rats and the underlying mechanisms. We found that daily retrieval of methamphetamine-associated memories 1 h before extinction sessions decreased subsequent drug priming-induced reinstatement, spontaneous recovery, and renewal of methamphetamine seeking. We also found that retrieval of methamphetamine-associated memories induced neuronal activation in the basolateral amygdala (BLA), while presenting extinction within the time window of reconsolidation abolished the neuronal activation in BLA. These results indicate that the CS memory retrieval-extinction procedure could prevent reconsolidation of methamphetamine memory traces in BLA and subsequent methamphetamine craving and relapse.
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