ArticleReproductive medicine and biology2019
Clinical outcomes of transfer of frozen and thawed single blastocysts derived from nonpronuclear and monopronuclear zygotes.
Article in Reproductive medicine and biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07666243 (Outcomes of Embryos Created From Abnormally Fertilized Oocytes), which is not on this map. Cited by 15 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Outcomes of Embryos Created From Abnormally Fertilized Oocytes
Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.
- Reconsidering the clinical value of 1PN-derived embryos: a systematic review and meta-analysis.Journal of assisted reproduction and genetics · 2025Pooled it
- A randomised control trial on oral dydrogesteroneJournal of medicine and life · 2023Trial
- Clinical outcomes of 1PN- and 3PN-derived blastocysts in the absence of transferable 2PN embryos: A retrospective analysis.PloS one · 2026Article
- The Istanbul consensus update: a revised ESHRE/ALPHA consensus on oocyte and embryo static and dynamic morphological assessment†,‡.Human reproduction (Oxford, England) · 2025Article
- Could blastocysts derived from abnormal fertilized zygotes be used? A systematic review and meta-analysis.European journal of obstetrics & gynecology and reproductive biology: X · 2025Review
- Developmental potential of non- and mono-pronuclear zygotes and associated clinical outcomes in IVF cycles.Frontiers in endocrinology · 2024Article
- Clinical outcomes of frozen-thawed blastocysts from zygotes with no or one pronucleus for in vitro fertilization and intracytoplasmic sperm injection cycles.Archives of gynecology and obstetrics · 2023Article
- Does the cell number of 0PN embryos on day 3 affect pregnancy and neonatal outcomes following single blastocyst transfer?BMC pregnancy and childbirth · 2022Article
- Development of a Model Predicting the Outcome ofFrontiers in endocrinology · 2022Article
- Time-lapse monitoring of fertilized human oocytes focused on the incidence of 0PN embryos in conventional in vitro fertilization cycles.Scientific reports · 2021Article
- Comparison of the rates for reaching the blastocyst stage between normal and abnormal pronucleus embryos monitored by a time-lapse system in IVF patientsJournal of the Turkish German Gynecological Association · 2021Article
- When embryology meets genetics: the definition of developmentally incompetent preimplantation embryos (DIPE)-the consensus of two Italian scientific societies.Journal of assisted reproduction and genetics · 2021Article
- Chromosome analysis of blastocysts derived from single pronuclear zygotes by array CGH and clinical outcomes by the transfer of single pronuclear zygotes.Journal of assisted reproduction and genetics · 2020Article
- Cell number considerations for blastocyst transfer in younger patients.Journal of assisted reproduction and genetics · 2020Article
- Clinical outcomes of transfer of frozen and thawed single blastocysts derived from nonpronuclear and monopronuclear zygotes.Reproductive medicine and biology · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
17 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeIn assisted reproductive technology, normal zygotes are bipronuclear (2PN) during fertilization confirmation; however, sometimes, nonpronuclear zygotes (0PN) and monopronuclear zygotes (1PN) are found during routine observations.
methodsTo elucidate the clinical usefulness of
resultsThe rates of pregnancy and live birth for 1PN-derived blastocysts obtained by conventional
conclusionsBoth 1PN- and 0PN-derived blastocysts can be used for embryo transfer; however, care should be taken in making decisions about 1PN-derived blastocysts, especially if they are obtained by ICSI.
Indexed as
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.