Evidence map›Paper›PMID 31312076›Full record

ArticleBioinformation2019

Molecular docking based design of Dengue NS5 methyltransferase inhibitors.

Mohd Adnan Kausar, Abrar Ali, Samir Qiblawi, Sma Shahid, Mohammad Asrar Izhari, Anamika Saral

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Bioinformation, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.7field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 8 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Mohd Adnan KausarCollege of Medicine, University of Hail, Hail, KSA.
Abrar AliCollege of Medicine, University of Hail, Hail, KSA.
Samir QiblawiCollege of Medicine, University of Hail, Hail, KSA.
Sma ShahidCollege of Medicine, University of Hail, Hail, KSA.
Mohammad Asrar IzhariDepartment of Laboratory Medicine College of Applied Medical Science, Al-Baha University, Saudi Arabia.
Anamika SaralSchool of studies in Biotechnology, Jiwaji University, Gwalior, Madhya Pradesh, India.
University of Ha'il · SAAl Baha University · SAJiwaji University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dengue is a viral infection caused by RNA infection of the family Flaviviridae and spread by the Aedes mosquitoes. Dengue NS5 methyltransferase is a known drug target for the disease. Therefore, it is of interest to design potential inhibitors for the target using molecular docking analysis. Our analysis shows the binding of compounds STOCK1N-98943, STOCK1N-98872, STOCK1N-98956, STOCK1N-98865, and STOCK1N-98950 with the protein drug target with optimal binding features for further in vitro and in vivo evaluations.

Indexed as

DengueIBSmethyltransferasemolecular dockingvirtual Screening

Identifiers

PMID31312076
PMCPMC6614123
OpenAlexW2955524482

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.