Evidence map›Paper›PMID 31311963›Full record

ArticleScientific reports2019

Deep-dose: a voxel dose estimation method using deep convolutional neural network for personalized internal dosimetry.

Min Sun Lee, Donghwi Hwang, Joong Hyun Kim, Jae Sung Lee

Abstract read
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.

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49citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

49 citing papers in PubMed.

  1. Article
  2. Applications of artificial intelligence in nuclear medicine.Zeitschrift fur medizinische Physik · 2026
    Review
  3. Swin UNETR-based prediction of [BMC medical imaging · 2026
    Article
  4. Review
  5. Design and validation of a deep learning GAN for predictingJournal of applied clinical medical physics · 2026
    Article
  6. Article
  7. Review
  8. Review
  9. Article
  10. The Role of Artificial Intelligence in Theranostics.Journal of nuclear medicine technology · 2025
    Review
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Review
  18. Monte Carlo methods for medical imaging research.Biomedical engineering letters · 2024
    Review
  19. Review
  20. Review
4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

4 authors.

Min Sun LeeDepartment of Nuclear Medicine, College of Medicine, Seoul National University, Seoul, 03080, Korea.
Donghwi HwangDepartment of Nuclear Medicine, College of Medicine, Seoul National University, Seoul, 03080, Korea.
Joong Hyun KimCenter for Ionizing Radiation, Korea Research Institute of Standards and Sciences, Daejeon, 34113, Korea.
Jae Sung LeeDepartment of Nuclear Medicine, College of Medicine, Seoul National University, Seoul, 03080, Korea. jaes@snu.ac.kr.ORCID http://orcid.org/0000-0001-7623-053X

Funding

National Research Foundation of Korea (NRF) NRF-2014M3C7034000National Research Foundation of Korea (NRF) NRF-2016R1A2B3014645
6 · The paper itself

Abstract

Personalized dosimetry with high accuracy is crucial owing to the growing interests in personalized medicine. The direct Monte Carlo simulation is considered as a state-of-art voxel-based dosimetry technique; however, it incurs an excessive computational cost and time. To overcome the limitations of the direct Monte Carlo approach, we propose using a deep convolutional neural network (CNN) for the voxel dose prediction. PET and CT image patches were used as inputs for the CNN with the given ground truth from direct Monte Carlo. The predicted voxel dose rate maps from the CNN were compared with the ground truth and dose rate maps generated voxel S-value (VSV) kernel convolution method, which is one of the common voxel-based dosimetry techniques. The CNN-based dose rate map agreed well with the ground truth with voxel dose rate errors of 2.54% ± 2.09%. The VSV kernel approach showed a voxel error of 9.97% ± 1.79%. In the whole-body dosimetry study, the average organ absorbed dose errors were 1.07%, 9.43%, and 34.22% for the CNN, VSV, and OLINDA/EXM dosimetry software, respectively. The proposed CNN-based dosimetry method showed improvements compared to the conventional dosimetry approaches and showed results comparable with that of the direct Monte Carlo simulation with significantly lower calculation time.

Identifiers

PMID31311963
PMCPMC6635490

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.