Evidence map›Paper›PMID 31311824›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2019

Circular RNA

Fangfang Wu, Bing Han, Shusheng Wu, Li Yang, Shuo Leng, Mingyue Li, Jiefeng Liao, Guangtian Wang, Qingqing Ye, Yuan Zhang and 7 more

Open access · bronzeAbstract readMulticenter Study
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 106 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
106citing papers in PubMed, 4 pooled it
10.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

106 citing papers in PubMed, 4 syntheses or guidelines pooled it, 202 citations in OpenAlex.

  1. Pooled it
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  4. Pooled it
  5. Review
  6. Article
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  8. METTL16 Promotes Cerebral Ischemia-Reperfusion Injury via mInternational journal of general medicine · 2026
    Article
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  10. CD8Cellular & molecular immunology · 2025
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46 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 7 institutions in 3 countries.

Fangfang WuDepartment of Pharmacology, School of Medicine, Southeast University, Nanjing, 210009, Jiangsu, China.
Bing HanDepartment of Pharmacology, School of Medicine, Southeast University, Nanjing, 210009, Jiangsu, China.
Shusheng WuDepartment of Pharmacology, School of Medicine, Southeast University, Nanjing, 210009, Jiangsu, China.
Li YangDepartment of Pharmacology, School of Medicine, Southeast University, Nanjing, 210009, Jiangsu, China.
Shuo LengDepartment of Radiology, School of Medicine, Southeast University, Nanjing, 210009, Jiangsu, China.
Mingyue LiDepartment of Pharmacology, School of Medicine, Southeast University, Nanjing, 210009, Jiangsu, China.
Jiefeng LiaoDepartment of Pharmacology, School of Medicine, Southeast University, Nanjing, 210009, Jiangsu, China.
Guangtian WangDepartment of Pharmacology, School of Medicine, Southeast University, Nanjing, 210009, Jiangsu, China.
Qingqing YeDepartment of Pharmacology, School of Medicine, Southeast University, Nanjing, 210009, Jiangsu, China.
Yuan ZhangDepartment of Pharmacology, School of Medicine, Southeast University, Nanjing, 210009, Jiangsu, China.
Haifeng ChenDepartment of Neurology, Affiliated Drum Tower Hospital, and Jiangsu Key Laboratory for Molecular Medicine, Nanjing University Medical School, Nanjing, 210008, Jiangsu, China.
Xufeng ChenEmergency Department, Jiangsu Province Hospital and Nanjing Medical University First Affiliated Hospital, Nanjing, 210029, Jiangsu, China.
Ming ZhongDepartment of Biochemistry, School of Medicine, Southeast University, Nanjing, 210009, Jiangsu, China.
Yun XuDepartment of Neurology, Affiliated Drum Tower Hospital, and Jiangsu Key Laboratory for Molecular Medicine, Nanjing University Medical School, Nanjing, 210008, Jiangsu, China.
Qiang LiuDepartment of Neurobiology, Barrow Neurological Institute, Phoenix, Arizona 85013.
John H ZhangDepartment of Physiology, School of Medicine, Loma Linda University, Loma Linda, California 92354, and.ORCID 0000-0002-4319-4285
Honghong YaoDepartment of Pharmacology, School of Medicine, Southeast University, Nanjing, 210009, Jiangsu, China, yaohh@seu.edu.cn.
Southeast University · CNNanjing Drum Tower Hospital · CNBarrow Neurological Institute · USJiangsu Province Hospital · CNLoma Linda University · USSoutheast University · BDZhongda Hospital Southeast University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Circular RNAs (circRNAs) are expressed at high levels in the brain and are involved in various CNS diseases. However, the potential role of circRNAs in ischemic stroke-associated neuronal injury remains largely unknown. Here, we investigated the important functions of circRNA

Indexed as

AgedAnimalsBrain IschemiaFemaleGene Knockdown TechniquesHumansMaleMiceMice, Inbred C57BLMicroRNAsMiddle AgedNeuronsNucleoside Transport ProteinsPoly(ADP-ribose) PolymerasesProtein Serine-Threonine KinasesRNA, CircularMicroRNAsMIRN335 microRNA, humanNucleoside Transport ProteinsPoly(ADP-ribose) PolymerasesProtein Serine-Threonine KinasesRNA, CircularTiPARP protein, humanTLK1 protein, humancircular RNA TLK1miR-335neuronal injurystrokeTIPARP

Identifiers

PMID31311824
PMCPMC6759031
OpenAlexW2957989634

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.