SynthesisViruses2019
Evaluation of an Immunochromatographic Assay as a Canine Rabies Surveillance Tool in Goa, India.
Synthesis in Viruses, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed.
- High sensitivity of the Bionote Anigen Rapid Rabies Antigen Test in detection of diverse rabies virus variants suggests utility for global rabies control.Journal of clinical microbiology · 2026Article
- LFD implementation uncovers hidden rabies burden: Pre- and post-implementation analysis and comparison with non-implementation sites in the Philippines.One health (Amsterdam, Netherlands) · 2025Article
- Rabies elimination in India: Pathways from vision to reality.The Indian journal of medical research · 2025Article
- Integrated Community-Based Reporting and Field Diagnostics for Improved Rabies Surveillance in Rural Laikipia, Kenya.Zoonoses and public health · 2025Article
- Evaluating Rabies Test Accuracy: A Systematic Review and Meta-Analysis of Human and Canine Diagnostic Methods.Diagnostics (Basel, Switzerland) · 2025Review
- First report on dog bite epidemiology and Rabies diagnosis in stray dogs: a one health study from Puducherry.Frontiers in veterinary science · 2025Article
- Combining genomics and epidemiology to investigate a zoonotic outbreak of rabies in Romblon Province, Philippines.Nature communications · 2024Article
- Investigating the Impact That Diagnostic Screening with Lateral Flow Devices Had on the Rabies Surveillance Program in Zanzibar, Tanzania.Microorganisms · 2024Article
- Recent updates on laboratory diagnosis of rabies.The Indian journal of medical research · 2024Review
- Evaluation of lateral flow devices for postmortem rabies diagnosis in animals in the Philippines: a multicenter study.Journal of clinical microbiology · 2023Article
- Evaluation of a real-time mobile PCR device (PCR 1100) for the detection of the rabies gene in field samples.Tropical medicine and health · 2023Article
- From Field Tests to Molecular Tools-Evaluating Diagnostic Tests to Improve Rabies Surveillance in Namibia.Viruses · 2023Article
- United Against Rabies Forum: The first 2 years.Frontiers in public health · 2023Review
- Elimination of human rabies in Goa, India through an integrated One Health approach.Nature communications · 2022Article
- Development of a Kit for Rapid Immunochromatographic Detection of Sacbrood Virus InfectingViruses · 2021Article
- Lateral flow devices for samples collected by straw sampling method for postmortem canine rabies diagnosis.PLoS neglected tropical diseases · 2021Article
- Capacity Building Efforts for Rabies Diagnosis in Resource-Limited Countries in Sub-Saharan Africa: A Case Report of the Central Veterinary Laboratory in Benin (Parakou).Frontiers in veterinary science · 2021Article
- Human rabies: prospects for elimination.CAB reviews : perspectives in agriculture, veterinary science, nutrition and natural resources · 2021Article
- Evaluation of the diagnostic accuracy of lateral flow devices as a tool to diagnose rabies in post-mortem animals.PLoS neglected tropical diseases · 2020Article
- Evaluation of a rapid immunochromatographic test kit to the gold standard fluorescent antibody test for diagnosis of rabies in animals in Bhutan.BMC veterinary research · 2020Article
Corrections and comments
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Authors and funding
15 authors.
Funding
Abstract
Rabies is a fatal zoonotic disease transmitted by the bite of a rabid animal. More than 95% of the human rabies cases in India are attributed to exposure to rabid dogs. This study evaluated the utility of a lateral flow immunochromatographic assay (LFA) (Anigen Rapid Rabies Ag Test Kit, Bionote, Hwaseong-si, Korea) for rapid post mortem diagnosis of rabies in dogs. Brain tissue was collected from 202 animals that were screened through the Government of Goa rabies surveillance system. The brain tissue samples were obtained from 188 dogs, nine cats, three bovines, one jackal and one monkey. In addition, 10 dogs that died due to trauma from road accidents were included as negative controls for the study. The diagnostic performance of LFA was evaluated using results from direct fluorescence antibody test (dFT); the current gold standard post mortem test for rabies infection. Three samples were removed from the analysis as they were autolysed and not fit for testing by dFT. Of the 209 samples tested, 117 tested positive by LFA and 92 tested negative, while 121 tested positive by dFT and 88 tested negative. Estimates of LFA sensitivity and specificity were 0.96 (95% CI 0.91-0.99) and 0.99 (95% CI 0.94-1.00), respectively. The LFA is a simple and low-cost assay that aids in the rapid diagnosis of rabies in the field without the need for expensive laboratory equipment or technical expertise. This study found that Bionote LFA has potential as a screening tool in rabies endemic countries.
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