Evidence map›Paper›PMID 31311135›Full record

ArticleInternational journal of molecular sciences2019

Acid- and Volume-Sensitive Chloride Currents in Microglial Cells.

Michael Kittl, Katharina Helm, Marlena Beyreis, Christian Mayr, Martin Gaisberger, Martina Winklmayr, Markus Ritter, Martin Jakab

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Identification of the Acid-Sensitive Site Critical for Chloral Hydrate (CH) Activation of the Proton-Activated Chloride Channel.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023
    Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Glial Chloride Channels in the Function of the Nervous System Across Species.Advances in experimental medicine and biology · 2021
    Article
  10. Review
  11. Acid- and Volume-Sensitive Chloride Currents in Human Chondrocytes.Frontiers in cell and developmental biology · 2020
    Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Michael KittlInstitute of Physiology and Pathophysiology, Paracelsus Medical University, 5020 Salzburg, Austria.
Katharina HelmInstitute of Physiology and Pathophysiology, Paracelsus Medical University, 5020 Salzburg, Austria.
Marlena BeyreisInstitute of Physiology and Pathophysiology, Paracelsus Medical University, 5020 Salzburg, Austria.
Christian MayrInstitute of Physiology and Pathophysiology, Paracelsus Medical University, 5020 Salzburg, Austria.
Martin GaisbergerInstitute of Physiology and Pathophysiology, Paracelsus Medical University, 5020 Salzburg, Austria.ORCID 0000-0002-3757-5612
Martina WinklmayrInstitute of Physiology and Pathophysiology, Paracelsus Medical University, 5020 Salzburg, Austria.
Markus RitterInstitute of Physiology and Pathophysiology, Paracelsus Medical University, 5020 Salzburg, Austria.
Martin JakabInstitute of Physiology and Pathophysiology, Paracelsus Medical University, 5020 Salzburg, Austria. martin.jakab@pmu.ac.at.ORCID 0000-0003-2110-5090
Paracelsus Medical University · ATUniversity of Salzburg · AT

Funding

Paracelsus Medizinische Privatuniversität E-17/26/137-JAK
6 · The paper itself

Abstract

Many cell types express an acid-sensitive outwardly rectifying (ASOR) anion current of an unknown function. We characterized such a current in BV-2 microglial cells and then studied its interrelation with the volume-sensitive outwardly rectifying (VSOR) Cl

Indexed as

Action PotentialsAnimalsCell LineChloride ChannelsChloridesHydrogen-Ion ConcentrationIodineIon TransportMiceMicrogliaOsmotic PressureChloride ChannelsChloridesIodineacidicanionchlorideCl− currentmicrogliapHRVDswelling-activatedvolume regulation

Identifiers

PMID31311135
PMCPMC6678294
OpenAlexW2956980668

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.