Evidence map›Paper›PMID 31311074›Full record

SynthesisInternational journal of environmental research and public health2019

The Association between Bisphenol A Exposure and Obesity in Children-A Systematic Review with Meta-Analysis.

Ka Young Kim, Eunil Lee, Yanghee Kim

Registry-linked trialAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in International journal of environmental research and public health, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07560579 (Weight Loss and Endocrine Disrupting Chemicals), which is not on this map. Cited by 41 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07560579 naactive not recruitingnot on this mapstarted 2025, after this paper: background citation

Weight Loss and Endocrine Disrupting Chemicals (EDCs): Lifestyle Interventions to Lose Weight and Reduce EDC Exposure in Individuals With Overweight/Obesity

TypeinterventionalSponsorMillion Marker Wellness, Inc.Ran2025 to 2026Enrolled226ConditionsObesity &Amp, Amp, Amp, OverweightArmsEducational curriculum, Weight loss Application, Urinary EDC metabolite testing, Siphox clinic biomarker test, Weight loss reporting
3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Epigenetic Mechanisms in Childhood Obesity.Annals of the New York Academy of Sciences · 2025
    Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Evaluation of Cat Exposure to Bisphenol A (BPA) Using Hair Sample Analysis.Animals : an open access journal from MDPI · 2026
    Article
  6. Article
  7. Review
  8. Review
  9. Article
  10. Review
  11. Endocrine disruptors, obesity, and metabolic syndrome.Turkish journal of medical sciences · 2025
    Review
  12. Review
  13. Review
  14. Dietary bisphenols exposure as an influencing factor of body mass index.Environmental health : a global access science source · 2024
    Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Ka Young KimDepartment of Nursing, College of Nursing, Gachon University, 191 Hambakmoeiro, Yeonsu-gu, Incheon City 21936, Korea.ORCID 0000-0003-3705-6449
Eunil LeeDepartment of Preventive Medicine, College of Medicine, Korea University, 73 Inchon-ro, Seongbuk-gu, Seoul 02841, Korea. eunil@korea.ac.kr.
Yanghee KimDepartment of Preventive Medicine, College of Medicine, Korea University, 73 Inchon-ro, Seongbuk-gu, Seoul 02841, Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bisphenol A (BPA) is an environmental chemical that has adverse effects on health, probably causing childhood obesity. However, this association remains controversial, and it is difficult to find evidence for direct causality between environmental exposure and disease using epidemiological studies. In this study, we sought to elucidate the possible causality between BPA exposure and childhood obesity by conducting two meta-analyses showing bidirectional associations, including exposure effect by obesity and obesity risk by exposure. Articles published up to September 2017 were searched in PubMed, Embase, and Cochrane Library. We evaluated observational studies that included measurements of urinary BPA concentration and BMI or body weight. Of 436 articles, a total of 13 studies were included in the meta-analysis. Two meta-analyses were performed to investigate the association between BPA exposure and childhood obesity. The results showed that the relatively high-exposed group had a significantly higher risk of childhood obesity than the relatively low-exposed group (odds ratio = 1.566, 95% confidence interval [CI]: 1.097 to 2.234,

Indexed as

Benzhydryl CompoundsBisphenol A CompoundsChildEnvironmental ExposureEnvironmental PollutantsHumansOdds RatioPediatric ObesityPhenolsRisk FactorsBenzhydryl Compoundsbisphenol ABisphenol A CompoundsEnvironmental PollutantsPhenolsBisphenol A (BPA)childhoodmeta-analysisobesitysystematic review

Identifiers

PMID31311074
PMCPMC6678763

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.