Evidence map›Paper›PMID 31310943›Full record

ArticleBiosensors & bioelectronics2019

Unprecedented peroxidase-mimicking activity of single-atom nanozyme with atomically dispersed Fe-N

Xiangheng Niu, Qiurong Shi, Wenlei Zhu, Dong Liu, Hangyu Tian, Shaofang Fu, Nan Cheng, Suiqiong Li, Jordan N Smith, Dan Du and 1 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biosensors & bioelectronics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
12.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 276 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Nanozymes Integrated Biochips Toward Smart Detection System.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Review
  5. Article
  6. Article
  7. Biomedical Applications of Nanozymes: An Enzymology Perspective.Angewandte Chemie (International ed. in English) · 2025
    Review
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  13. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Xiangheng NiuSchool of Mechanical and Materials Engineering, Washington State University, Pullman, WA, 99164, USA.
Qiurong ShiSchool of Mechanical and Materials Engineering, Washington State University, Pullman, WA, 99164, USA.
Wenlei ZhuSchool of Mechanical and Materials Engineering, Washington State University, Pullman, WA, 99164, USA.
Dong LiuSchool of Mechanical and Materials Engineering, Washington State University, Pullman, WA, 99164, USA.
Hangyu TianSchool of Mechanical and Materials Engineering, Washington State University, Pullman, WA, 99164, USA.
Shaofang FuSchool of Mechanical and Materials Engineering, Washington State University, Pullman, WA, 99164, USA.
Nan ChengSchool of Mechanical and Materials Engineering, Washington State University, Pullman, WA, 99164, USA.
Suiqiong LiSchool of Mechanical and Materials Engineering, Washington State University, Pullman, WA, 99164, USA.
Jordan N SmithHealth Impacts & Exposure Science, Pacific Northwest National Laboratory, Richland, WA, 99352, USA.
Dan DuSchool of Mechanical and Materials Engineering, Washington State University, Pullman, WA, 99164, USA. Electronic address: annie.du@wsu.edu.
Yuehe LinSchool of Mechanical and Materials Engineering, Washington State University, Pullman, WA, 99164, USA. Electronic address: yuehe.lin@wsu.edu.
Washington State University · USPacific Northwest National Laboratory · US

Funding

ACL HHS R01OH011023NIOSH CDC HHS R01 OH011023
6 · The paper itself

Abstract

Due to robustness, easy large-scale preparation and low cost, nanomaterials with enzyme-like characteristics (defined as 'nanozymes') are attracting increasing interest for various applications. However, most of currently developed nanozymes show much lower activity in comparison with natural enzymes, and the deficiency greatly hinders their use in sensing and biomedicine. Single-atom catalysts (SACs) offer the unique feature of maximum atomic utilization, providing a potential pathway to improve the catalytic activity of nanozymes. Herein, we propose a Fe-N-C single-atom nanozyme (SAN) that exhibits unprecedented peroxidase-mimicking activity. The SAN consists of atomically dispersed Fe─N

Indexed as

AnimalsBiomimetic MaterialsBiosensing TechniquesButyrylcholinesteraseCarbonCatalysisHorsesIronMetal-Organic FrameworksPeroxidasePorosityButyrylcholinesteraseCarbonIronMetal-Organic FrameworksPeroxidaseActivityButyrylcholinesteraseMetal-organic frameworkNanozymePeroxidase mimicSingle-atom catalysis

Identifiers

PMID31310943
PMCPMC8672370
OpenAlexW2959158634

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.