ArticleMitochondrion2019
Complex I and II are required for normal mitochondrial Ca
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Article in Mitochondrion, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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0cells of the map it votes in
17citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
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Who cites it
17 citing papers in PubMed, 33 citations in OpenAlex.
- InsP3R signaling and actomyosin-dependent mitochondrial dynamics play essential roles in mitochondrial stress-induced longevity.Nature communications · 2026Article
- Dietary bile acids supplementation reduces eggshell translucency and improves eggshell quality in late-phase laying hens.Poultry science · 2026Article
- InsP3R signaling mediates mitochondrial stress-induced longevity through actomyosin-dependent mitochondrial dynamics.bioRxiv : the preprint server for biology · 2025Article
- Mitochondrial CaJournal of cellular physiology · 2025Review
- Postbiotic Parabacteroides Distasonis Supplementation Enhances Intestinal and Skeletal Muscle Function in Aged Mice.Aging and disease · 2025Article
- The flexible chain: regulation of structure and activity of ETC complexes defines rate of ATP synthesis and sites of superoxide generation.Biophysical reviews · 2025Review
- The IPBiochimica et biophysica acta. Molecular basis of disease · 2025Article
- Mitochondrial Calcium Regulation of Cardiac Metabolism in Health and Disease.Physiology (Bethesda, Md.) · 2024Review
- Mitochondrial division inhibitor (mdivi-1) induces extracellular matrix (ECM)-detachment of viable breast cancer cells by a DRP1-independent mechanism.Scientific reports · 2024Article
- Respiratory Complex I dysfunction in cancer: from a maze of cellular adaptive responses to potential therapeutic strategies.The FEBS journal · 2022Review
- Genetic impairment of succinate metabolism disrupts bioenergetic sensing in adrenal neuroendocrine cancer.Cell reports · 2022Article
- Mitochondrial calcium uniporter stabilization preserves energetic homeostasis during Complex I impairment.Nature communications · 2022Article
- Mitochondrial dysfunction induces radioresistance in colorectal cancer by activating [CaCell death & disease · 2021Article
- Inhibition of InsP3R with Xestospongin B Reduces Mitochondrial Respiration and Induces Selective Cell Death in T Cell Acute Lymphoblastic Leukemia Cells.International journal of molecular sciences · 2021Article
- A looming role of mitochondrial calcium in dictating the lung epithelial integrity and pathophysiology of lung diseases.Mitochondrion · 2020Review
- Is Mitochondrial Dysfunction a Common Root of Noncommunicable Chronic Diseases?Endocrine reviews · 2020Review
- The Two-Way Relationship Between Calcium and Metabolism in Cancer.Frontiers in cell and developmental biology · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors at 6 institutions in 2 countries.
Fabian JañaDepartamento de Ciencias de la Salud, Universidad de Aysén, Coyhaique, Chile; Geroscience Center for Brain Health and Metabolism, Santiago, Chile.
Galdo BustosGeroscience Center for Brain Health and Metabolism, Santiago, Chile; Center for Integrative Biology, Faculty of Sciences, Universidad Mayor, Santiago, Chile.
José RivasDepartamento de Ciencias de la Salud, Universidad de Aysén, Coyhaique, Chile; Program of Cellular and Molecular Biology, Institute of Biomedical Sciences (ICBM), Faculty of Medicine, Universidad de Chile, Santiago, Chile.
Pablo CruzGeroscience Center for Brain Health and Metabolism, Santiago, Chile; Program of Cellular and Molecular Biology, Institute of Biomedical Sciences (ICBM), Faculty of Medicine, Universidad de Chile, Santiago, Chile.
Felix UrraGeroscience Center for Brain Health and Metabolism, Santiago, Chile; Molecular and Clinical Pharmacology Program, Institute of Biomedical Sciences, Faculty of Medicine, University of Chile, Santiago, Chile.
Carla Basualto-AlarcónDepartamento de Ciencias de la Salud, Universidad de Aysén, Coyhaique, Chile; Geroscience Center for Brain Health and Metabolism, Santiago, Chile; Anatomy and Legal Medicine Department, Faculty of Medicine, University of Chile, Santiago, Chile.
Eduardo SagredoCentro de Investigación y Tratamiento del Cáncer, Facultad de Medicina, Universidad de Chile, Chile.
Melany RíosGeroscience Center for Brain Health and Metabolism, Santiago, Chile.
Alenka LovyGeroscience Center for Brain Health and Metabolism, Santiago, Chile; Center for Integrative Biology, Faculty of Sciences, Universidad Mayor, Santiago, Chile; Center for Neuroscience Research, Tufts University School of Medicine, Boston, MA, USA.
Zhiwei DongDepartment of Medicine, Center for Precision Medicine, University of Texas Health San Antonio, TX, USA.
Oscar CerdaProgram of Cellular and Molecular Biology, Institute of Biomedical Sciences (ICBM), Faculty of Medicine, Universidad de Chile, Santiago, Chile; Millennium Nucleus of Ion Channels-Associated Diseases (MiNICAD), Santiago, Chile.; The Wound Repair, Treatment and Health (WoRTH), Chile.
Muniswamy MadeshDepartment of Medicine, Center for Precision Medicine, University of Texas Health San Antonio, TX, USA. Electronic address: muniswamy@uthscsa.edu.
César CárdenasGeroscience Center for Brain Health and Metabolism, Santiago, Chile; Center for Integrative Biology, Faculty of Sciences, Universidad Mayor, Santiago, Chile; Buck Institute for Research on Aging, Novato, CA, USA; Department of Chemistry and Biochemistry, University of California, Santa Barbara, CA, United States. Electronic address: julio.cardenas@umayor.cl.
Center for Climate and Resilience Research · CLUniversidad Mayor · CLThe University of Texas Health Science Center at San Antonio · USMillennium Nucleus of Ion Channel Associated Diseases · CLUniversidad de Aysén · CLUniversity of Chile · CL
Funding
TUSM/T-NEMC CENTER FOR NEUROSCIENCE RESEARCH - Imaging CoreP30NS047243 · NINDS · TUFTS UNIVERSITY BOSTON · PI JACKSON, F ROB · 2003 to 2017
$10.0MCoordination of Pathophysiologic Endothelial Cell Signaling by ROSR01HL086699 · NHLBI · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI MUNISWAMY, MADESH · 2008 to 2018
$4.3MSpectral revelations of mitochondrial Ca2+ flux interactomeR01GM109882 · NIGMS · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI MUNISWAMY, MADESH · 2014 to 2022
$3.3MControl of Endothelial Mechanotransduction by the Mitochondrial Ca2+ Uniporter: Implications for AtherosclerosisR01HL142673 · NHLBI · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI ALEVRIADOU, BARBARA RITA, MUNISWAMY, MADESH · 2018 to 2021
$2.0MInhibition of MCUR1-MCU mediated mitochondrial Ca2+ uptake prevents I/R injuryR01HL119306 · NHLBI · TEMPLE UNIV OF THE COMMONWEALTH · PI MUNISWAMY, MADESH · 2014 to 2017
$1.6MMultiphoton Confocal Microscopy for Biomedical ResearchS10RR027327 · NCRR · TEMPLE UNIV OF THE COMMONWEALTH · PI MUNISWAMY, MADESH · 2010 to 2010
$500kNCRR NIH HHS S10 RR027327NHLBI NIH HHS R01 HL086699NHLBI NIH HHS R01 HL119306NHLBI NIH HHS R01 HL142673NIGMS NIH HHS R01 GM109882NINDS NIH HHS P30 NS047243
Abstract
Cytosolic calcium (
Indexed as
HomeostasisCalciumElectron Transport Complex IHumansMCF-7 CellsMembrane Potential, MitochondrialMitochondriaMitochondrial ProteinsSuccinate DehydrogenaseCalciumElectron Transport Complex IMitochondrial ProteinsNDUFAF3 protein, humanSDHB protein, humanSuccinate DehydrogenaseCalcium fluxCell deathMigrationMitochondrial membrane potential
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.