ArticleEmerging infectious diseases2019
Congenital Syphilis as a Measure of Maternal and Child Healthcare, Brazil.
Article in Emerging infectious diseases, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
30 citing papers in PubMed, 1 synthesis or guideline pooled it, 101 citations in OpenAlex.
- Computational methods applied to syphilis: where are we, and where are we going?Frontiers in public health · 2023Pooled it
- Temporal trend of syphilis in pregnancy and congenital syphilis by race.Clinics (Sao Paulo, Brazil) · 2026Article
- The role of STORCH infections in shaping neurodevelopment: a longitudinal case-control study in preterm children.BMC pediatrics · 2026Article
- Resilience paths: maternal experiences in coping with syphilis exposure or congenital infection and the role of support networks.BMC pregnancy and childbirth · 2026Article
- Spatial analysis of mortality due to congenital syphilis in Brazil from 2008 to 2022.PloS one · 2026Article
- Assessing progress towards the elimination of mother-to-child transmission of syphilis in Peru: A national retrospective analysis.PLOS global public health · 2026Article
- Hospitalizations for congenital infections in Brazil's unified health system: nationwide trends and regional disparities, 2008-2024.Antimicrobial stewardship & healthcare epidemiology : ASHE · 2026Article
- Congenital syphilis and oral involvement: Treponema pallidum detection and oral development in exposed children.Einstein (Sao Paulo, Brazil) · 2026Observational
- Temporal trends of the incidence rate of syphilis during pregnancy and congenital syphilis in São Paulo, Brazil, 2011-2023.Epidemiologia e servicos de saude : revista do Sistema Unico de Saude do Brasil · 2025Article
- [Effect of positive deviation on the diagnosis and treatment of gestational syphilis, and the prevention of congenital syphilis: A cohort study].Revista colombiana de obstetricia y ginecologia · 2024Article
- Sociodemographic and clinical characteristics associated with maternal and congenital syphilis - A prospective study in Peru.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2024Article
- Epidemiology of Syphilis in Pregnancy and Congenital Syphilis in Brazil and the Risk or Associated Factors: Protocol for a Systematic Review.JMIR research protocols · 2024Article
- Prevalence of bacterial vaginosis, sexually transmitted infections and their association with HPV infections in asymptomatic women attending antenatal care in Ethiopia.Ecancermedicalscience · 2024Article
- Congenital syphilis, syphilis in pregnancy and prenatal care in Brazil: An ecological study.PloS one · 2024Article
- Sociodemographic and Clinical Factors for Microcephaly Secondary to Teratogenic Infections in Brazil: An Ecological Study.Viruses · 2023Observational
- Incidence and associated factors of congenital syphilis at a tertiary care center in Thailand.Asian biomedicine : research, reviews and news · 2023Article
- Evaluation of massive education in prison health: a perspective of health care for the person deprived of freedom in Brazil.Frontiers in public health · 2023Article
- Congenital syphilis in Switzerland: a marker of inequality? A mini-review.Frontiers in public health · 2023Review
- Clinical Protocols and Treatment Guidelines for the Management of Maternal and Congenital Syphilis in Brazil and Portugal: Analysis and Comparisons: A Narrative Review.International journal of environmental research and public health · 2022Review
- Quality of life, depressive symptoms, anxiety, and sexual function in mothers of neonates with congenital syphilis in the Northeast Brazil: A cohort study.Lancet regional health. Americas · 2022Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Syphilis is a sexually transmitted infection that has direct adverse effects on maternal and infant health through vertical Treponema pallidum transmission during early pregnancy. We evaluated congenital syphilis as a predictor of the quality of basic maternal and child healthcare in Brazil during 2010-2015. We investigated case rates and correlations with epidemiologic and socioeconomic indicators. We observed rising congenital syphilis incidence rates and increasing syphilis-associated perinatal and infant mortality rates in all regions. Case rates were highest in the Northeast, Southeast, and South, and congenital syphilis infant mortality rates were highest in the Northeast and Southeast. We observed correlations between congenital syphilis rates and infant death, spontaneous abortion (miscarriage), and stillbirth rates. We also noted correlations between rates of stillbirth caused by syphilis and inadequate prenatal care. Our study suggests gaps in basic healthcare for pregnant women and indicates the urgent need for measures to increase early diagnosis and appropriate treatment.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.