ArticleMicrobial genomics2019
Domestication of Campylobacter jejuni NCTC 11168.
Article in Microbial genomics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed.
- Butyric glycerides enhance resistance of chicken enterocytes to pathogen adhesion and cytotoxicity in vitro.Veterinary research communications · 2026Article
- Growth rates and metabolic traits differ by diarrhoeal manifestation inJournal of medical microbiology · 2025Article
- Small worms big discoveries:Frontiers in cellular and infection microbiology · 2025Review
- Machine learning to attribute the source of Campylobacter infections in the United States: A retrospective analysis of national surveillance data.The Journal of infection · 2024Article
- Activation of the l-fucose utilization cluster inHeliyon · 2024Article
- The ATCC genome portal: 3,938 authenticated microbial reference genomes.Microbiology resource announcements · 2024Article
- Synergistic phenotypic adaptations of motile purple sulphur bacteria Chromatium okenii during lake-to-laboratory domestication.PloS one · 2024Article
- Development and validation of a CRISPR interference system for gene regulation in Campylobacter jejuni.BMC microbiology · 2022Article
- Article
- Differences in the Propensity of Different Antimicrobial Resistance Determinants to Be Disseminated via Transformation inMicroorganisms · 2022Article
- Local accessory gene sharing among EgyptianMicrobial genomics · 2022Article
- Article
- Comparative Analysis of L-Fucose Utilization and Its Impact on Growth and Survival ofFrontiers in microbiology · 2022Article
- Genome diversity of domesticatedMicrobial genomics · 2022Article
- Complete genome forMicrobial genomics · 2021Article
- Quantifying bacterial evolution in the wild: A birthday problem for Campylobacter lineages.PLoS genetics · 2021Article
- Campylobacter jejuni genotypes are associated with post-infection irritable bowel syndrome in humans.Communications biology · 2021Article
- Genomic epidemiology of Campylobacter jejuni associated with asymptomatic pediatric infection in the Peruvian Amazon.PLoS neglected tropical diseases · 2020Article
- Agricultural intensification and the evolution of host specialism in the enteric pathogenProceedings of the National Academy of Sciences of the United States of America · 2020Article
- Role of Cecal Microbiota in the Differential Resistance of Inbred Chicken Lines to Colonization byApplied and environmental microbiology · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
32 authors.
Funding
Abstract
Reference and type strains of well-known bacteria have been a cornerstone of microbiology research for decades. The sharing of well-characterized isolates among laboratories has run in parallel with research efforts and enhanced the reproducibility of experiments, leading to a wealth of knowledge about trait variation in different species and the underlying genetics. Campylobacter jejuni strain NCTC 11168, deposited at the National Collection of Type Cultures in 1977, has been adopted widely as a reference strain by researchers worldwide and was the first Campylobacter for which the complete genome was published (in 2000). In this study, we collected 23 C. jejuni NCTC 11168 reference isolates from laboratories across the UK and compared variation in simple laboratory phenotypes with genetic variation in sequenced genomes. Putatively identical isolates, identified previously to have aberrant phenotypes, varied by up to 281 SNPs (in 15 genes) compared to the most recent reference strain. Isolates also display considerable phenotype variation in motility, morphology, growth at 37 °C, invasion of chicken and human cell lines, and susceptibility to ampicillin. This study provides evidence of ongoing evolutionary change among C. jejuni isolates as they are cultured in different laboratories and highlights the need for careful consideration of genetic variation within laboratory reference strains. This article contains data hosted by Microreact.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.